Evidence map›Paper›PMID 29053951›Full record

ArticleCell chemical biology2017

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.

Zhijun Guo, Irina F Sevrioukova, Ilia G Denisov, Xia Zhang, Ting-Lan Chiu, Dafydd G Thomas, Eric A Hanse, Rebecca A D Cuellar, Yelena V Grinkova, Vanessa Wankhede Langenfeld and 27 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Cell chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors.

Zhijun Guo
Irina F Sevrioukova
Ilia G Denisov
Xia Zhang
Ting-Lan Chiu
Dafydd G Thomas
Eric A Hanse
Rebecca A D Cuellar
Yelena V Grinkova
Vanessa Wankhede Langenfeld
Daniel S Swedien
Justin D Stamschror
Juan Alvarez
Fernando Luna
Adela Galván
Young Kyung Bae
Julia D Wulfkuhle
Rosa I Gallagher
Emanuel F Petricoin
Beverly Norris
Craig M Flory
Robert J Schumacher
M Gerard O'Sullivan
Qing Cao
Haitao Chu
John D Lipscomb
William M Atkins
Kalpna Gupta
Ameeta Kelekar
Ian A Blair
Jorge H Capdevila
John R Falck
Stephen G Sligar
Thomas L Poulos
Gunda I Georg
Elizabeth Ambrose
David A Potter

Funding

Nanoscale Approaches to Understanding Membrane Protein FunctionR35GM118145 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI STEPHEN G. SLIGAR · 2016 to 2026
$7.5M
NIGMS NIH HHS R35 GM118145
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.