Evidence map›Paper›PMID 29053927›Full record

ReviewExpert opinion on drug safety2018

Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder.

Nicholas T Bello, Bryn L Yeomans

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on drug safety, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Bulimia nervosa.Nature reviews. Disease primers · 2026
    Review
  5. Review
  6. Pharmacological management of binge eating disorder.The mental health clinician · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Current Discoveries and Future Implications of Eating Disorders.International journal of environmental research and public health · 2023
    Review
  12. Review
  13. Eating Disorders and Metabolic Diseases.International journal of environmental research and public health · 2023
    Review
  14. Article
  15. Psychopharmacologic Management of Eating Disorders.Current psychiatry reports · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. A review of binge eating disorder and obesity.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas T Belloa Department of Animal Sciences, Nutritional Sciences Graduate Program , Rutgers, The State University of New Jersey , New Brunswick , NJ , USA.
Bryn L Yeomansa Department of Animal Sciences, Nutritional Sciences Graduate Program , Rutgers, The State University of New Jersey , New Brunswick , NJ , USA.
Rutgers, The State University of New Jersey · US

Funding

Method optimization and validation to assess the in vivo bioavailability and metabolism of raspberry ketoneR01AT008933 · NCCIH · RUTGERS, THE STATE UNIV OF N.J. · PI BELLO, NICHOLAS T · 2017 to 2021
$1.8M
NCCIH NIH HHS R01 AT008933
6 · The paper itself

Abstract

introductionEating disorders represent a set of psychiatric illnesses with lifelong complications and high relapse rates. Individuals with eating disorders are often stigmatized and clinicians have a limited set of treatments options. Pharmacotherapy has the potential to improve long term compliance and patient commitment to treatment for eating disorders. AREAS COVERED: This review will examine the efficacy and safety profile of the FDA-approved medications for the treatment of bulimia nervosa (BN) and binge eating disorder (BED). This will include the evaluation of fluoxetine for BN, and lisdexamfetamine for BED. Safety information will be review from randomized control trials (RCT), open label trials, and case reports. EXPERT OPINION: Fluoxetine for BN and lisdexamfetamine for BED are relatively safe and well-tolerated. Despite these properties, these two medications represent a limited arsenal for the pharmacological treatment of eating disorders. Thus, more research-based strategies are needed to develop safe, effective, and more targeted therapies for eating disorders.

Indexed as

Binge-Eating DisorderBulimia NervosaFluoxetineHumansLisdexamfetamine DimesylateMedication AdherenceRandomized Controlled Trials as TopicFluoxetineLisdexamfetamine Dimesylatebulimicloss of controlProzactherapeuticvyvanse

Identifiers

PMID29053927
PMCPMC6095708
OpenAlexW2765566375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.