Evidence map›Paper›PMID 29053447›Full record

ArticleIEEE transactions on medical imaging2018

Multimodal MR Synthesis via Modality-Invariant Latent Representation.

Agisilaos Chartsias, Thomas Joyce, Mario Valerio Giuffrida, Sotirios A Tsaftaris

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 326 citations in OpenAlex.

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  10. Unified Cross-Modal Medical Image Synthesis With Hierarchical Mixture of Product-of-Experts.IEEE transactions on pattern analysis and machine intelligence · 2026
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Agisilaos Chartsias
Thomas Joyce
Mario Valerio Giuffrida
Sotirios A Tsaftaris
University of Edinburgh · GBIMT School for Advanced Studies Lucca · ITThe Alan Turing Institute · GB

Funding

Reliable Evaluation of Coronary Artery Disease using Myocardial BOLD MRI with CO2R01HL091989 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DHARMAKUMAR, ROHAN · 2008 to 2016
$3.5M
An Accurate Non-Contrast-Enhanced Cardiac MRI Method for Imaging Chronic Myocardial Infarctions: Technical Developments to Rapid Clinical ValidationR01HL136578 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI LI, DEBIAO · 2017 to 2020
$3.4M
NHLBI NIH HHS R01 HL091989NHLBI NIH HHS R01 HL136578
6 · The paper itself

Abstract

We propose a multi-input multi-output fully convolutional neural network model for MRI synthesis. The model is robust to missing data, as it benefits from, but does not require, additional input modalities. The model is trained end-to-end, and learns to embed all input modalities into a shared modality-invariant latent space. These latent representations are then combined into a single fused representation, which is transformed into the target output modality with a learnt decoder. We avoid the need for curriculum learning by exploiting the fact that the various input modalities are highly correlated. We also show that by incorporating information from segmentation masks the model can both decrease its error and generate data with synthetic lesions. We evaluate our model on the ISLES and BRATS data sets and demonstrate statistically significant improvements over state-of-the-art methods for single input tasks. This improvement increases further when multiple input modalities are used, demonstrating the benefits of learning a common latent space, again resulting in a statistically significant improvement over the current best method. Finally, we demonstrate our approach on non skull-stripped brain images, producing a statistically significant improvement over the previous best method. Code is made publicly available at https://github.com/agis85/multimodal_brain_synthesis.

Indexed as

AlgorithmsBrainHumansImage Processing, Computer-AssistedMachine LearningMagnetic Resonance ImagingMultimodal ImagingNeural Networks, Computer

Identifiers

PMID29053447
PMCPMC5904017
OpenAlexW2767044624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.