Evidence map›Paper›PMID 29053273›Full record

ArticleInorganic chemistry2017

Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory.

Zach N Nilsson, Brian L Mandella, Kakali Sen, Demet Kekilli, Michael A Hough, Pierre Moënne-Loccoz, Richard W Strange, Colin R Andrew

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zach N NilssonDepartment of Chemistry and Biochemistry, Eastern Oregon University , La Grande, Oregon 97850, United States.
Brian L MandellaDepartment of Chemistry and Biochemistry, Eastern Oregon University , La Grande, Oregon 97850, United States.
Kakali SenSchool of Biological Sciences, University of Essex , Colchester Essex, CO4 3SQ, United Kingdom.
Demet KekilliSchool of Biological Sciences, University of Essex , Colchester Essex, CO4 3SQ, United Kingdom.
Michael A HoughSchool of Biological Sciences, University of Essex , Colchester Essex, CO4 3SQ, United Kingdom.
Pierre Moënne-LoccozDivision of Environmental and Biomolecular Systems, Oregon Health and Science University , Portland, Oregon 97239, United States.ORCID http://orcid.org/0000-0002-7684-7617
Richard W StrangeSchool of Biological Sciences, University of Essex , Colchester Essex, CO4 3SQ, United Kingdom.
Colin R AndrewDepartment of Chemistry and Biochemistry, Eastern Oregon University , La Grande, Oregon 97850, United States.ORCID http://orcid.org/0000-0001-5908-012X
University of Essex · GBEastern Oregon University · USOregon Health & Science University · US

Funding

Nitric Oxide Reactions in MetalloenzymesR01GM074785 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MOENNE-LOCCOZ, PIERRE · 2006 to 2019
$3.8M
NIGMS NIH HHS R01 GM074785
6 · The paper itself

Abstract

Nitrite coordination to heme cofactors is a key step in the anaerobic production of the signaling molecule nitric oxide (NO). An ambidentate ligand, nitrite has the potential to coordinate via the N- (nitro) or O- (nitrito) atoms in a manner that can direct its reactivity. Distinguishing nitro vs nitrito coordination, along with the influence of the surrounding protein, is therefore of particular interest. In this study, we probed Fe(III) heme-nitrite coordination in Alcaligenes xylosoxidans cytochrome c' (AXCP), an NO carrier that excludes anions in its native state but that readily binds nitrite (K

Indexed as

AlcaligenesCoordination ComplexesCytochromes c'HemeIronLigandsModels, ChemicalMolecular StructureNitritesPoint MutationSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanCoordination ComplexesCytochromes c'HemeIronLigandsNitrites

Identifiers

PMID29053273
PMCPMC5677563
OpenAlexW2765206688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.