ArticlePaediatric and perinatal epidemiology2018
Trends in Risk of Pregnancy Loss Among US Women, 1990-2011.
Article in Paediatric and perinatal epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 2 of them syntheses that pooled it.
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Who cites it
93 citing papers in PubMed, 2 syntheses or guidelines pooled it, 212 citations in OpenAlex.
- Prophylactic antibiotics for uterine evacuation procedures to manage miscarriage.The Cochrane database of systematic reviews · 2025Pooled it
- The landscape of recurrent spontaneous abortion registered on clinical trials.gov.Frontiers in endocrinology · 2024Pooled it
- Pregnancy Outcomes after Exposure to Tuberculosis Treatment in Phase 3 Clinical Trial, 2016-2020.Emerging infectious diseases · 2025Trial
- Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial.Lancet (London, England) · 2023Trial
- The Sierra Leone Trial to Introduce a Vaccine Against Ebola: An Evaluation of rVSV∆G-ZEBOV-GP Vaccine Tolerability and Safety During the West Africa Ebola Outbreak.The Journal of infectious diseases · 2018Trial
- Assessing the Risk of Adverse Maternal and Infant Outcomes Following Prenatal Modafinil Exposure: A French Nationwide Cohort Study.Drug safety · 2026Article
- Per- and polyfluoroalkyl substances, perceived stress, and miscarriage risk in a cohort of US Black women.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Pregnancy occurrence, intendedness, and outcomes among U.S. females with and without disability, 2011-2019.Disability and health journal · 2026Article
- Humoral pregnancy analyses reveal strategies for fetal protection and aberrancy in miscarriage.Cell reports. Medicine · 2026Article
- Contribution of Consumer Products to Emerging Chemical Exposures in a Preconception Cohort Study.Environmental science & technology · 2026Article
- Spontaneous miscarriage and later lifestyle in predicting hazard of premature mortality: a cohort study in UK Biobank.Archives of gynecology and obstetrics · 2026Article
- Dynamic Associations between Ambient PMEnvironment & health (Washington, D.C.) · 2026Article
- Article
- Trends in Risk of Pregnancy Loss Among US Women by Metropolitan Status, 2000-2018.Paediatric and perinatal epidemiology · 2025Article
- Racial and Ethnic Representation in Studies of Psychological Trauma During Pregnancy in the United States.Journal of racial and ethnic health disparities · 2025Review
- Assessing Change in Medical Management of Early Pregnancy Loss before and after Implementation of a Learning Collaborative for Initiation of Mifepristone Use.Maternal and child health journal · 2025Article
- Gynecologic and obstetric complications in women with congenital fibrinogen disorders: insights from the Prospective Rare Bleeding Disorders Database.Research and practice in thrombosis and haemostasis · 2025Article
- Pregnancy and Infant Outcomes in Women with Multiple Sclerosis Exposed to Glatiramer Acetate Therapy: An Extended 4-Year Safety Update.Drug safety · 2025Article
- Exploring Potential Biomarkers in Recurrent Pregnancy Loss: A Literature Review of Omics Studies to Molecular Mechanisms.International journal of molecular sciences · 2025Review
- Contraception use and pregnancy in women receiving a 2-dose Ebola vaccine in Rwanda: A retrospective analysis of UMURINZI vaccination campaign data.PLoS medicine · 2025Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPregnancy loss can have physical and psychological consequences for women and their families. Though a previous study described an increase in the risk of self-reported pregnancy loss from 1970 to 2000, more recent examinations from population-based data of US women are lacking.
methodsWe used data from the 1995, 2002, 2006-2010, 2011-2015 National Survey of Family Growth on self-reported pregnancy loss (miscarriage, stillbirth, ectopic pregnancy) among US women (15-44 years) who reported at least one pregnancy conceived during 1990-2011 that did not result in induced termination (n = 20 012 women; n = 42 526 pregnancies). Trends in the risk of self-reported pregnancy loss and early pregnancy loss (<12 weeks) were estimated, separately, by year of pregnancy conception (limited to 1990-2011 to ensure a sufficient sample of pregnancies for each year and maternal age group) using log-Binomial and Poisson models, adjusted for maternal- and pregnancy-related factors.
resultsAmong all self-reported pregnancies, excluding induced terminations, the risk of pregnancy loss was 19.7% and early pregnancy loss was 13.5% during 1990-2011. Risk of pregnancy loss increased by a relative 2% (rate ratio [RR] 1.02, 95% confidence interval [CI] 1.01, 1.02) per year in unadjusted models and 1% per year (RR 1.01, 95% CI 1.00, 1.02) during 1990-2011, after adjustment for maternal characteristics and pregnancy-related factors. In general, trends were similar for early pregnancy loss.
conclusionFrom 1990 to 2011, risk of self-reported pregnancy loss increased among US women. Further work is needed to better understand the drivers of this increase in reported pregnancy loss in the US.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.