Evidence map›Paper›PMID 29052795›Full record

ArticleInflammopharmacology2018

Effects of glutamine, taurine and their association on inflammatory pathway markers in macrophages.

Talita Sartori, Guilherme Galvão Dos Santos, Amanda Nogueira-Pedro, Edson Makiyama, Marcelo Macedo Rogero, Primavera Borelli, Ricardo Ambrósio Fock

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Taurine corrects lupus CD4Nutrition & metabolism · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Taurine AlleviatesFrontiers in immunology · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Talita SartoriDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil.
Guilherme Galvão Dos SantosDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil.
Amanda Nogueira-PedroDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil.
Edson MakiyamaDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil.
Marcelo Macedo RogeroDepartment of Nutrition, School of Public Health, University of São Paulo, São Paulo, Brazil.
Primavera BorelliDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil.
Ricardo Ambrósio FockDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bloco 17, Butantã, São Paulo, SP, 05508-000, Brazil. hemato@usp.br.
Universidade de São Paulo · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/16463-8
6 · The paper itself

Abstract

The immune system is essential for the control and elimination of infections, and macrophages are cells that act as important players in orchestrating the various parts of the inflammatory/immune response. Amino acids play important role in mediating functionality of the inflammatory response, especially mediating macrophages functions and cytokines production. We investigated the influence of glutamine, taurine and their association on the modulation of inflammatory pathway markers in macrophages. The RAW 264.7 macrophage cell line was cultivated in the presence of glutamine and taurine and proliferation rates, cell viability, cell cycle phases, IL-1α, IL-6, IL-10 and TNF-α as well as H

Indexed as

AnimalsCell SurvivalDose-Response Relationship, DrugDrug SynergismGlutamineInflammation MediatorsMacrophagesMiceRAW 264.7 CellsTaurineGlutamineInflammation MediatorsTaurineCytokinesGlutamineMacrophagesNFκBTaurine

Identifiers

PMID29052795
OpenAlexW2766532970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.