Evidence map›Paper›PMID 29052309›Full record

SynthesisObesity reviews : an official journal of the International Association for the Study of Obesity2018

Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence.

M Zheng, K E Lamb, C Grimes, R Laws, K Bolton, K K Ong, K Campbell

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed, 13 pooled it
37.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

233 citing papers in PubMed, 13 syntheses or guidelines pooled it, 391 citations in OpenAlex.

  1. Identifying Key Predictors of Mid-Childhood Obesity in a Population-Based Cohort Study: An Evidence Synthesis and Predictive Modeling Study.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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  3. Higher versus lower protein intake in formula-fed term infants.The Cochrane database of systematic reviews · 2023
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  5. Integrative Review of Mental Health and Feeding Styles in Parents of Bottle-Fed Infants.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2023
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173 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

M ZhengSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
K E LambSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
C GrimesSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
R LawsSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
K BoltonSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
K K OngMedical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
K CampbellSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia.
Deakin University · AUUniversity of Cambridge · GB

Funding

Medical Research Council MC_UU_12015/2
6 · The paper itself

Abstract

The contribution of rapid weight gain (RWG) during infancy to later adiposity has received considerable investigation. The present systematic review and meta-analysis aimed to update the literature on association between RWG and subsequent adiposity outcomes. Electronic searches were undertaken in EMBASE, MEDLINE, psycINFO, PubMed and ScienceDirect. Studies that examined the associations between RWG (a change in weight z-scores > 0.67) during infancy (from birth to age 2 years) and subsequent adiposity outcomes were included. Random effects meta-analysis was conducted to obtain the weighted-pooled estimates of the odds of overweight/obesity for those with RWG. Seventeen studies were eligible for inclusion with the majority of studies (15/17) being of high/acceptable quality and reporting positive associations between RWG during infancy and later adiposity outcomes. RWG in infancy was associated with overweight/obesity from childhood to adulthood (pooled odds ratio = 3.66, 95% confidence interval: 2.59-5.17, I

Indexed as

AdiposityChildChild DevelopmentChild Nutritional Physiological PhenomenaHumansInfantInfant Nutritional Physiological PhenomenaLife StylePediatric ObesityProspective StudiesRisk FactorsTime FactorsWeight GainAdiposityinfancyoverweight riskrapid weight gain

Identifiers

PMID29052309
PMCPMC6203317
OpenAlexW2766911199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.