Evidence map›Paper›PMID 29052123›Full record

ArticleClinical journal of gastroenterology2017

Successful chemotherapy with modified FOLFIRINOX for pancreatic acinar cell carcinoma.

Minami Hashimoto, Takuto Hikichi, Tomohiro Suzuki, Mayumi Tai, Osamu Ichii, Nobuo Matsuhashi, Eisaku Kita, Shintaro Takahashi, Yoshinori Okubo, Hando Hakozaki and 2 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Metastatic pancreatic acinar cell carcinoma withJournal of gastrointestinal oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Minami HashimotoDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Takuto HikichiDepartment of Endoscopy, Fukushima Medical University Hospital, 1 Hikarigaoka, Fukushima, 960-1295, Japan. takuto@fmu.ac.jp.ORCID http://orcid.org/0000-0002-9815-1557
Tomohiro SuzukiDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Mayumi TaiDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Osamu IchiiDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Nobuo MatsuhashiDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Eisaku KitaDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Shintaro TakahashiDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Yoshinori OkuboDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Hando HakozakiDepartment of Pathology, Fukushima Rosai Hospital, Iwaki, Japan.
Yutaka EjiriDepartment of Gastroenterology, Fukushima Rosai Hospital, Iwaki, Japan.
Hiromasa OhiraDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Japan Organization of Occupational Health and Safety · JPFukushima Medical University · JPFukushima Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal ultrasonography revealed a pancreatic mass in a 67-year-old man with diabetes mellitus. Endoscopic ultrasound-guided fine needle aspiration led to the histological diagnosis of acinar cell carcinoma. The clinical stage was determined to be IVb based on findings of multiple metastatic lesions in the liver and lymph nodes, as well as splenic vein infiltration. Because the patient was not a surgical candidate, he underwent chemotherapy with modified FOLFIRINOX. In the absence of any severe adverse events, 12 courses of chemotherapy were delivered, resulting in marked shrinkage of both the primary and metastatic lesions. The outcome was judged to be a partial response, which was maintained even 9 months from the introduction of the chemotherapy. The results of this case suggest that modified FOLFIRINOX is safe and effective in the treatment of pancreatic acinar cell carcinoma.

Indexed as

AgedAntineoplastic Combined Chemotherapy ProtocolsEndoscopic Ultrasound-Guided Fine Needle AspirationEndosonographyHumansMalePancreatic NeoplasmsTomography, X-Ray ComputedAcinar cell carcinomaChemotherapyEndoscopic ultrasound-guided fine needle aspirationModified FOLFIRINOXPancreatic cancer

Identifiers

PMID29052123
OpenAlexW2767076235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.