Evidence map›Paper›PMID 29052077›Full record

ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2017

Beat-to-beat blood pressure and heart rate responses to the Valsalva maneuver.

David S Goldstein, William P Cheshire

Open access · greenAbstract readReview
In one paragraph

Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 78 citations in OpenAlex.

  1. Trial
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  8. Review
  9. Article
  10. In at the deep end: the physiological challenges associated with artistic swimming.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  11. Central αThe Journal of physiology · 2024
    Article
  12. Article
  13. On the accuracy of sequence methods for baroreflex sensitivity estimation.Physical and engineering sciences in medicine · 2024
    Article
  14. Review
  15. Tilt-evoked, breathing-driven blood pressure oscillations: Independence from baroreflex-sympathoneural function.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Observational
  16. Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

David S GoldsteinClinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike MSC-1620, Building 10 Room 5N220, Bethesda, MD, 20892, USA. goldsteind@ninds.nih.gov.
William P CheshireDepartment of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.
Mayo Clinic in Florida · USNational Institutes of Health · US

Funding

Biomarkers of Parkinson Disease and Related DisordersZIANS003034 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2009 to 2025
$22.8M
Mechanisms of Parkinson Disease and Related DisordersZIANS003033 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2009 to 2022
$8.2M
Biomarkers of Parkinson Disease and Related DisordersZ01NS003034 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2007 to 2008
$3.9M
Mechanisms of Parkinson Disease and Related DisordersZ01NS003033 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2007 to 2008
$966k
Neurocardiology: Catecholamine Systems In Stress and DisZ01NS002979 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID S · 1999 to 2006
–
Intramural NIH HHS Z01 NS002979Intramural NIH HHS Z01 NS003033Intramural NIH HHS Z01 NS003034Intramural NIH HHS Z99 NS999999Intramural NIH HHS ZIA NS003033Intramural NIH HHS ZIA NS003034NINDS NIH HHS 1ZIANS003034
6 · The paper itself

Abstract

Measurement of beat-to-beat blood pressure and heart rate responses to the Valsalva maneuver is the basis for a highly informative autonomic function test. Whereas in the past this measurement required intra-arterial cannulation, the development of finger cuff devices that acquire arterial pressure waveforms indistinguishable from those recorded intra-arterially has made it possible to obtain accurate measurements noninvasively. In a patient with orthostatic hypotension, the pattern of blood pressure responses during and after the release of the maneuver can identify a neurogenic basis: sympathetic neurocirculatory failure. The quantifiable change in cardiac interbeat interval per unit change in systolic pressure during the maneuver can identify baroreflex-cardiovagal failure.

Indexed as

AgingAnimalsBaroreflexBlood PressureHeart RateHumansHypotension, OrthostaticValsalva ManeuverAutonomicBlood pressureParasympatheticSympatheticValsalva

Identifiers

PMID29052077
PMCPMC8897824
OpenAlexW2765282022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.