Evidence map›Paper›PMID 29052038›Full record

ArticleJournal of the American Society for Mass Spectrometry2018

Proof of Concept Coded Aperture Miniature Mass Spectrometer Using a Cycloidal Sector Mass Analyzer, a Carbon Nanotube (CNT) Field Emission Electron Ionization Source, and an Array Detector.

Jason J Amsden, Philip J Herr, David M W Landry, William Kim, Raul Vyas, Charles B Parker, Matthew P Kirley, Adam D Keil, Kristin H Gilchrist, Erich J Radauscher and 13 more

Abstract read
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In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Concept and simulation of a MEMS cycloidal mass analyzer.Microsystems & nanoengineering · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jason J AmsdenDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Philip J HerrDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
David M W LandryDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
William KimDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Raul VyasDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Charles B ParkerDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Matthew P KirleyDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Adam D KeilBroadway Analytical, LLC, Monmouth, IL, 61462, USA.
Kristin H GilchristEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
Erich J RadauscherDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Stephen D HallEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
James B CarlsonEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
Nicholas BaldasaroEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
David StokesEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
Shane T Di DonaDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Zachary E RussellDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Sonia GregoEngineering and Applied Physics Division, RTI International, Research Triangle Park, NC, 27709, USA.
Steven J EdwardsDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Roger P SperlineDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
M Bonner DentonDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Brian R StonerDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Michael E GehmDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
Jeffrey T GlassDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA. jeff.glass@duke.edu.

Funding

Advanced Research Projects Agency - Energy DE-AR0000546
6 · The paper itself

Abstract

Despite many potential applications, miniature mass spectrometers have had limited adoption in the field due to the tradeoff between throughput and resolution that limits their performance relative to laboratory instruments. Recently, a solution to this tradeoff has been demonstrated by using spatially coded apertures in magnetic sector mass spectrometers, enabling throughput and signal-to-background improvements of greater than an order of magnitude with no loss of resolution. This paper describes a proof of concept demonstration of a cycloidal coded aperture miniature mass spectrometer (C-CAMMS) demonstrating use of spatially coded apertures in a cycloidal sector mass analyzer for the first time. C-CAMMS also incorporates a miniature carbon nanotube (CNT) field emission electron ionization source and a capacitive transimpedance amplifier (CTIA) ion array detector. Results confirm the cycloidal mass analyzer's compatibility with aperture coding. A >10× increase in throughput was achieved without loss of resolution compared with a single slit instrument. Several areas where additional improvement can be realized are identified. Graphical Abstract ᅟ.

Indexed as

Carbon nanotubeCoded aperturesCycloidal mass analyzerIon array detectorMiniature mass spectrometer

Identifiers

PMID29052038

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.