Evidence map›Paper›PMID 29051779›Full record

ArticleObstetric medicine2017

Childhood maltreatment and inflammation among pregnant women with gestational diabetes mellitus: A pilot study.

Margaret Bublitz, Suzanne De La Monte, Susan Martin, Lucia Larson, Ghada Bourjeily

Abstract read
In one paragraph

Article in Obstetric medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Margaret BublitzWomen's Medicine Collaborative, The Miriam Hospital, USA.
Suzanne De La MonteDepartment of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, USA.
Susan MartinWomen's Medicine Collaborative, The Miriam Hospital, USA.
Lucia LarsonWomen's Medicine Collaborative, The Miriam Hospital, USA.
Ghada BourjeilyWomen's Medicine Collaborative, The Miriam Hospital, USA.

Funding

Placental role in mediating adverse outcomes in obstructive sleep apneaR01HD078515 · NICHD · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2014 to 2018
$2.7M
Predictors of de novo development of obstructive sleep apnea in pregnancyR01HL130702 · NHLBI · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2016 to 2020
$2.6M
NHLBI NIH HHS R01 HL130702NICHD NIH HHS R01 HD078515
6 · The paper itself

Abstract

backgroundWomen with childhood maltreatment histories are at increased risk for adverse birth outcomes. Mechanisms explaining this link are poorly understood. Past research is limited by sampling pregnant women at low risk for adverse maternal and neonatal outcomes.

methodsThis pilot study was a secondary data analysis of 24 women with gestational diabetes mellitus; 17% of the sample also reported a maltreatment history. Women provided a blood sample to measure inflammatory cytokines and insulin resistance, and saliva samples to measure diurnal cortisol. Birth outcomes for past and current pregnancies were recorded.

resultsHistories of maltreatment were associated with elevated interleukin-15 and a marginally greater incidence of preterm delivery in current and past pregnancies.

conclusionsThis pilot study was the first to demonstrate an association between childhood maltreatment history and inflammatory cytokine levels in pregnant women diagnosed with gestational diabetes mellitus.

Indexed as

gestational diabetesinflammationMaltreatmentpreterm birth

Identifiers

PMID29051779
PMCPMC5637996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.