Evidence map›Paper›PMID 29051759›Full record

ArticleFrontiers in immunology2017

IFNγ Enhances CD64-Potentiated Phagocytosis of

Kelly L Hawley, Adriana R Cruz, Sarah J Benjamin, Carson J La Vake, Jorge L Cervantes, Morgan LeDoyt, Lady G Ramirez, Daniza Mandich, Mary Fiel-Gan, Melissa J Caimano and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Putative mechanisms of ocular inflammation in syphilis.Journal of ophthalmic inflammation and infection · 2026
    Review
  3. Advancements in Syphilis Vaccine Development.Sexually transmitted diseases · 2026
    Article
  4. Review
  5. Article
  6. Review
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  9. Article
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  11. Observational
  12. Frontiers in cellular and infection microbiology · 2025
    Article
  13. Article
  14. Article
  15. Development and utilization ofbioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Immunodominant extracellular loops ofbioRxiv : the preprint server for biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Kelly L HawleyDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
Adriana R CruzCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Sarah J BenjaminDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
Carson J La VakeDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
Jorge L CervantesDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
Morgan LeDoytDepartment of Medicine, UConn Health, Farmington, CT, United States.
Lady G RamirezCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Daniza MandichDepartment of Pathology, Hartford Hospital, Hartford, CT, United States.
Mary Fiel-GanDepartment of Pathology, Hartford Hospital, Hartford, CT, United States.
Melissa J CaimanoDepartment of Medicine, UConn Health, Farmington, CT, United States.
Justin D RadolfDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
Juan C SalazarDepartment of Pediatrics, UConn Health, Farmington, CT, United States.
UConn Health · USCentro Internacional de Entrenamiento e Investigaciones Medicas · COHartford Hospital · USConnecticut Children's Medical Center · US

Funding

RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
Treponema pallidum Outer Membrane Proteins and Transition Metal AcquisitionR01AI026756 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI RADOLF, JUSTIN D · 1992 to 2017
$5.1M
Phagosomal Signals Shape Inflammatory Responses to B. BurgdorferiR01AI090166 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SALAZAR, JUAN C · 2011 to 2015
$2.1M
T.pallidum Membrane Immunogens and Anti-Oxidant DefenseR37AI026756 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2002 to 2006
$1.8M
RpoS Regulation of Borrelia burgdorferi Genes in vivoR56AI029735 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2012 to 2012
$536k
Mechanisms of Immune Evasion and Recognition in Human SyphilisR03TW009172 · FIC · CENTRO INTERNACIONAL (CIDEIM) · PI CRUZ, ADRIANA RAQUEL · 2013 to 2015
$142k
Systemic Innate Immune Responses in Secondary SyphilisR03TW008023 · FIC · CONNECTICUT CHILDREN'S MEDICAL CENTER · PI SALAZAR, JUAN C · 2008 to 2010
$116k
FIC NIH HHS R03 TW008023FIC NIH HHS R03 TW009172NIAID NIH HHS R01 AI026756NIAID NIH HHS R01 AI029735NIAID NIH HHS R01 AI090166NIAID NIH HHS R37 AI026756NIAID NIH HHS R56 AI029735
6 · The paper itself

Abstract

Syphilis is a multi-stage, sexually transmitted disease caused by the spirochete

Indexed as

Fcγ receptorhumanmacrophagephagocytosisphagosomal signalingTreponema pallidumvaccine model

Identifiers

PMID29051759
PMCPMC5633599
OpenAlexW2762280983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.