ArticleToxics2017
Cytotoxic and Inflammatory Potential of Air Samples from Occupational Settings with Exposure to Organic Dust.
Article in Toxics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Immunotoxicity of Inhalable Organic Dust Samples Based on In Vitro Analysis of Human Respiratory Epithelial Cells.International journal of molecular sciences · 2026Article
- Inflammatory responses of inhalable aerosols from powder food industry in THP-1 cells.Annals of work exposures and health · 2025Article
- Portuguese cork industry: filling the knowledge gap regarding occupational exposure to fungi and related health effects.Frontiers in public health · 2024Article
- Divergent TLR2 and TLR4 Activation by Fungal Spores and Species Diversity in Dust from Waste Sorting Plants.Applied and environmental microbiology · 2023Article
- Article
- The association of chronic bronchitis and airflow obstruction with lifetime and current farm activities in a sample of rural adults in Iowa.International archives of occupational and environmental health · 2022Article
- Review
- Cytotoxicity ofToxins · 2022Article
- Cytotoxicity ofJournal of fungi (Basel, Switzerland) · 2021Article
- Airborne occupational exposures and inflammatory biomarkers in the Lifelines cohort study.Occupational and environmental medicine · 2021Article
- Duration of exposure and educational level as predictors of occupational respiratory symptoms among adults in Ethiopia: A systematic review and meta-analysis.SAGE open medicine · 2021Review
- Assessment of Respiratory Problems in Workers Associated with Intensive Poultry Facilities in Pakistan.Safety and health at work · 2020Article
- Methacholine induced airway contraction in porcine precision cut lung slices from indoor and outdoor reared pigs.American journal of translational research · 2020Article
- Association Between Organic Dust Exposure and Adult-Asthma: A Systematic Review and Meta-Analysis of Case-Control Studies.Allergy, asthma & immunology research · 2019Article
- Occupational Exposure to Mycotoxins in Swine Production: Environmental and Biological Monitoring Approaches.Toxins · 2019Article
- Microbial Growth on Dust-Loaded Filtering Materials Used for the Protection of Respiratory Tract as a Factor Affecting Filtration Efficiency.International journal of environmental research and public health · 2018Article
- Dust at Various Workplaces-Microbiological and Toxicological Threats.International journal of environmental research and public health · 2018Article
- Article
- A new approach to assess occupational exposure to airborne fungal contamination and mycotoxins of forklift drivers in waste sorting facilities.Mycotoxin research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organic dust and related microbial exposures are the main inducers of several respiratory symptoms. Occupational exposure to organic dust is very common and has been reported in diverse settings. In vitro tests using relevant cell cultures can be very useful for characterizing the toxicity of complex mixtures present in the air of occupational environments such as organic dust. In this study, the cell viability and the inflammatory response, as measured by the production of pro-inflammatory cytokines tumor necrosis factor-α (TNFα) and interleukin-1 β (IL-1β), were determined in human macrophages derived from THP-1 monocytic cells. These cells were exposed to air samples from five occupational settings known to possess high levels of contamination of organic dust: poultry and swine feed industries, waste sorting, poultry production and slaughterhouses. Additionally, fungi and particle contamination of those settings was studied to better characterize the organic dust composition. All air samples collected from the assessed workplaces caused both cytotoxic and pro-inflammatory effects. The highest responses were observed in the feed industry, particularly in swine feed production. This study emphasizes the importance of measuring the organic dust/mixture effects in occupational settings and suggests that differences in the organic dust content may result in differences in health effects for exposed workers.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.