Evidence map›Paper›PMID 29051428›Full record

ArticleToxics2016

Association of Long-Term Pesticide Exposure and Biologic Parameters in Female Farm Workers in Tanzania: A Cross Sectional Study.

Wilbert Bunini Manyilizu, Robinson Hammerton Mdegela, Rudovick Kazwala, Hezron Nonga, Mette Muller, Elisabeth Lie, Eystein Skjerve, Jan Ludvig Lyche

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

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  10. Review
  11. Health effects associated with occupational exposure to hand-arm or whole body vibration.Journal of toxicology and environmental health. Part B, Critical reviews · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Wilbert Bunini ManyilizuDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P. O. Box 3021, Morogoro 023, Tanzania. wmanyilizu@gmail.com.
Robinson Hammerton MdegelaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P. O. Box 3021, Morogoro 023, Tanzania. rmdegela2012@gmail.com.
Rudovick KazwalaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P. O. Box 3021, Morogoro 023, Tanzania. kazwala@gmail.com.
Hezron NongaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P. O. Box 3021, Morogoro 023, Tanzania. nongahezron@yahoo.co.uk.
Mette MullerDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences, P. O. Box 8146, Oslo 454, Norway. mette.helen.bjorge.muller@nmbu.no.
Elisabeth LieDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences, P. O. Box 8146, Oslo 454, Norway. elisabeth.lie@niva.no.
Eystein SkjerveDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences, P. O. Box 8146, Oslo 454, Norway. eystein.skjerve@nmbu.no.
Jan Ludvig LycheDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences, P. O. Box 8146, Oslo 454, Norway. jan.l.lyche@nmbu.no.
Norwegian University of Life Sciences · NOSokoine University of Agriculture · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to assess the association of long-term pesticide exposure (≥5 years) with hematological, serum biochemical parameters and acetylcholinesterase activity in farm workers. These pesticides included organophosphorus pesticides, carbamates, pyrethroids, dithiocarbamates, and other pesticides such as endosulfan. Applying a cross-sectional study design, 69 females from a pesticide-exposed farm population and 30 females from a district not using pesticides (reference group) were studied. The mean red cell corpuscular volume and hematocrit values were significantly lower (74.7 ± 9.1 fl; 95% CI 72.5-76.9 and 32.0% ± 4.6%; 95% CI 30.9-33.1, respectively) in the exposed compared to the reference group, whereas mean corpuscular hemoglobin concentration and platelets were significantly higher (37.4 ± 3.8 g/dL; 95% CI 36.5-38.3 and 374.1 ± 95.3/L; 95% CI 351.2-396.9, respectively) in the exposed compared to the reference group. Mean serum glutamic oxaloacetate transaminase (20.7 ± 8.9 U/L; 95% CI 18.5-22.9) and creatinine (83.9 ± 6.6 μmol/L; 95% CI 82.3-85.5) were significantly higher in the exposed compared to the reference group. A higher mean esterase activity (AChE 0.6 ± 0.2 mM/min/mg protein; 95% CI 0.56-0.7; BChE 0.9 ± 0.4 mM/min/mg protein; 95% CI 0.9-1.1) was noted in the exposed group. Regression models suggest that occupational exposure (

Indexed as

acetylcholine esterase activitybiochemicaleffectshematologicalpesticides

Identifiers

PMID29051428
PMCPMC5606649
OpenAlexW2525115055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.