ArticleGenes & development2017
New genes often acquire male-specific functions but rarely become essential in
Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed.
- Adaptive deletion of functional duplicate genes in Drosophila.Journal of evolutionary biology · 2026Article
- Adaptive deletion of functional duplicate genes inbioRxiv : the preprint server for biology · 2025Article
- Systematic analysis of noncanonical ribosomal protein paralogs does not provide evidence for specialized functions inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Analysis of Transcript Expression and Core Promoter DNA Sequences of Brain, Adipose Tissues and Testis in Human and Fruit Fly.International journal of molecular sciences · 2025Article
- Evolutionary Analysis of Gene-Expression Localization in the Model Crustacean, Daphnia pulex.Molecular ecology · 2025Article
- Coincident evolution and functional adaptation of the taxonomically restricted genes ivph-3 and gon-14 in Caenorhabditis nematodes.Biology open · 2025Article
- Evolutionary Analysis of Gene-expression Localization in the Model Crustacean,bioRxiv : the preprint server for biology · 2025Article
- Evolutionary innovations in germline biology of placental mammals identified by transcriptomics of first-wave spermatogenesis in opossum.Developmental cell · 2025Article
- Diversification and recurrent adaptation of the synaptonemal complex in Drosophila.PLoS genetics · 2025Article
- Orphan genes are not a distinct biological entity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- MicroRNA-mediated network redundancy is constrained by purifying selection and contributes to expression robustness in Drosophila melanogaster.Communications biology · 2024Article
- The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis.eLife · 2024Article
- Sequence, Structure, and Functional Space of Drosophila De Novo Proteins.Genome biology and evolution · 2024Article
- The roles of gene duplications in the dynamics of evolutionary conflicts.Proceedings. Biological sciences · 2024Review
- Histone removal in sperm protects paternal chromosomes from premature division at fertilization.Science (New York, N.Y.) · 2023Article
- HP6/Umbrea is dispensable for viability and fertility, suggesting essentiality of newly evolved genes is rare.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Viruses in LaboratoryViruses · 2023Article
- Article
- Nuclear elongation during spermiogenesis depends on physical linkage of nuclear pore complexes to bundled microtubules by Drosophila Mst27D.PLoS genetics · 2023Article
- Evolution and implications of de novo genes in humans.Nature ecology & evolution · 2023Review
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Authors and funding
10 authors.
Funding
Abstract
Relatively little is known about the in vivo functions of newly emerging genes, especially in metazoans. Although prior RNAi studies reported prevalent lethality among young gene knockdowns, our phylogenomic analyses reveal that young
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.