Evidence map›Paper›PMID 29051307›Full record

ArticlePhysiological reports2017

Effect of renal denervation on urine angiotensinogen excretion in prenatally programmed rats.

Asifhusen Mansuri, Susan K Legan, Jyoti Jain, Issa Alhamoud, Jyothsna Gattineni, Michel Baum

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Asifhusen MansuriDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Susan K LeganDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Jyoti JainDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Issa AlhamoudDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Jyothsna GattineniDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Michel BaumDepartment of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas Michel.Baum@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal programming results in an increase in blood pressure in adult offspring. We have shown that compared to control adult offspring whose mothers were fed a 20% protein diet, programmed adults whose mothers were fed a 6% protein diet during the last half of pregnancy have an increase in renal sympathetic nerve activity and urinary angiotensinogen/creatinine levels. We hypothesized that the increase in urinary angiotensinogen was mediated by renal sympathetic nerve activity in programmed rats. In this study performed in 3 month old rats, renal denervation resulted in normalization of blood pressure in the 6% programmed group (150 ± 3 Hg in 6% sham vs. 121 ± 4 Hg in 6% denervated,

Indexed as

AngiotensinogenAnimalsBlood PressureCaloric RestrictionCreatinineDenervationFemaleFetal Growth RetardationHypertensionKidneyMaleRatsRats, Sprague-DawleyRenin-Angiotensin SystemSympathetic Nervous SystemAngiotensinogenCreatinineAngiotensinogenprenatal programmingrenal denervation

Identifiers

PMID29051307
PMCPMC5661239
OpenAlexW2765881553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.