Evidence map›Paper›PMID 29051217›Full record

Observational studyJournal of the American Heart Association2017

Management of Persistent Angina After Myocardial Infarction Treated With Percutaneous Coronary Intervention: Insights From the TRANSLATE-ACS Study.

Alexander C Fanaroff, Lisa A Kaltenbach, Eric D Peterson, Connie N Hess, David J Cohen, Gregg C Fonarow, Tracy Y Wang

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07380919 (Inhibition of Late Sodium Current), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07380919 phase2 / phase3recruitingnot on this mapstarted 2026, after this paper: background citation

Inhibition of Late Sodium Current (INa) to Prevent Coronary MICROvascular Dysfunction in Patients Presenting With ST-Elevation Myocardial Infarction and Multivessel Disease: A Multicenter, Randomized, Controlled and Open Label Study (INaMICRON Study)

TypeinterventionalSponsorFederico II UniversityRan2026 to 2026Enrolled100ConditionsSTEMI (ST Elevation MI)ArmsRanolazine
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  6. Observational
  7. Article
  8. Review
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  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Alexander C FanaroffDivision of Cardiology, Duke University, Durham, NC alexander.fanaroff@duke.edu.
Lisa A KaltenbachDuke Clinical Research Institute, Duke University, Durham, NC.
Eric D PetersonDivision of Cardiology, Duke University, Durham, NC.
Connie N HessDivision of Cardiology, University of Colorado, and CPC Clinical Research, Aurora, CO.
David J CohenSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO.
Gregg C FonarowAhmanson-UCLA Cardiomyopathy Center, University of California Los Angeles, CA.
Tracy Y WangDivision of Cardiology, Duke University, Durham, NC.
Duke University · USClinical Research Institute · USMeridian Clinical Research · USSaint Luke's Hospital · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAngina has important implications for patients' quality of life and healthcare utilization. Angina management after acute myocardial infarction (MI) treated with percutaneous coronary intervention (PCI) is unknown. METHODS AND

resultsTRANSLATE-ACS (Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) was a longitudinal study of MI patients treated with percutaneous coronary intervention at 233 US hospitals from 2010 to 2012. Among patients with self-reported angina at 6 weeks post-MI, we described patterns of angina and antianginal medication use through 1 year postdischarge. Of 10 870 percutaneous coronary intervention-treated MI patients, 3190 (29.3%) reported angina symptoms at 6 weeks post-MI; of these, 658 (20.6%) had daily/weekly angina while 2532 (79.4%) had monthly angina. Among patients with 6-week angina, 2936 (92.0%) received β-blockers during the 1 year post-MI, yet only 743 (23.3%) were treated with other antianginal medications. At 1 year, 1056 patients (33.1%) with 6-week angina reported persistent angina symptoms. Of these, only 31.2% had been prescribed non-β-blocker antianginal medications at any time in the past year. Among patients undergoing revascularization during follow-up, only 25.9% were on ≥1 non-β-blocker anti-anginal medication at the time of the procedure.

conclusionsAngina is present in one third of percutaneous coronary intervention-treated MI patients as early as 6 weeks after discharge, and many of these patients have persistent angina at 1 year. Non-β-blocker antianginal medications are infrequently used in these patients, even among those with persistent angina and those undergoing revascularization.

Indexed as

Percutaneous Coronary InterventionAgedAngina PectorisCardiovascular AgentsDrug PrescriptionsDrug Utilization ReviewFemaleHumansLongitudinal StudiesMaleMiddle AgedNon-ST Elevated Myocardial InfarctionPatient DischargePlatelet Aggregation InhibitorsPractice Patterns, Physicians'PrevalenceCardiovascular AgentsPlatelet Aggregation InhibitorsPurinergic P2Y Receptor Antagonistsangina pectorisguideline adherencemyocardial infarctionpatient reported outcomepercutaneous coronary intervention

Identifiers

PMID29051217
PMCPMC5721884
OpenAlexW2766319720

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.