ArticleJournal of the American Heart Association2017
Changes in Statin Adherence Following an Acute Myocardial Infarction Among Older Adults: Patient Predictors and the Association With Follow-Up With Primary Care Providers and/or Cardiologists.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Medication Adherence After Acute Coronary Syndrome in Women Compared With Men: A Systematic Review and Meta-Analysis.Frontiers in global women's health · 2021Pooled it
- The Use of SMS Text Messaging to Improve the Hospital-to-Community Transition in Patients With Acute Coronary Syndrome (Txt2Prevent): Results From a Pilot Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- The Statin Paradox: Drivers and Consequences of Therapy Discontinuation.Metabolites · 2026Review
- Adherence trajectories of oral lipid-lowering therapy in patients with myocardial infarction and its estimated impact on low-density lipoprotein levels.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Latent profile analysis for medication adherence in patients with chronic obstructive pulmonary disease.BMC pulmonary medicine · 2025Article
- Improving transitional care after acute myocardial infarction: A scoping review.Health care science · 2024Article
- Prevalence and associated factors of non-adherence to antihyperlipidemic medication: a nationwide cross sectional survey in Pakistan.Scientific reports · 2024Article
- Optimal P2YAmerican heart journal plus : cardiology research and practice · 2023Article
- The effect of statin adherence on patients with type 2 diabetes after percutaneous coronary intervention for acute coronary syndrome.Cardiovascular drugs and therapy · 2023Article
- Use of big data from health insurance for assessment of cardiovascular outcomes.Frontiers in artificial intelligence · 2023Review
- Lipid-Lowering Therapy Utilization and Dosage Among Patients with Acute Coronary Syndrome Events: A Retrospective Cohort from 12 Community Hospitals.Clinical epidemiology · 2023Article
- Association between sociodemographic factors and cholesterol-lowering medication use in U.S. adults post-myocardial infarction.PloS one · 2023Article
- Disparities by sex in P2YBMJ open · 2021Article
- Comparing Continuous and Binary Group-based Trajectory Modeling Using Statin Medication Adherence Data.Medical care · 2021Article
- Determinants of Non-Adherence to the Medications for Dyslipidemia: A Systematic Review.Patient preference and adherence · 2021Review
- Opening the black box of the group-based trajectory modeling process to analyze medication adherence patterns: An example using real-world statin adherence data.Pharmacoepidemiology and drug safety · 2020Article
- Change in Trajectories of Adherence to Lipid-Lowering Drugs Following Non-Fatal Acute Coronary Syndrome or Stroke.Journal of the American Heart Association · 2019Article
- Applying machine learning to predict real-world individual treatment effects: insights from a virtual patient cohort.Journal of the American Medical Informatics Association : JAMIA · 2019Article
- It's Not Too Late to Improve Statin Adherence: Association Between Changes in Statin Adherence from Before to After Acute Myocardial Infarction and All-Cause Mortality.Journal of the American Heart Association · 2019Observational
- A challenge for psychocardiology: Addressing the causes and consequences of patients' perceptions of enduring somatic threat.The American psychologist · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundHospitalizations for acute myocardial infarctions (AMIs) are associated with changes in statin adherence. It is unclear to what extent adherence changes, which patients are likely to change, and how post-discharge follow-up is associated with statin adherence change. METHODS AND
resultsThis retrospective study used Medicare data for all fee-for-service beneficiaries 66 years and older with an AMI hospitalization in 2008-2010 and statin use before their index AMI. Multivariable multinomial logistic regression models (odds ratio [OR] and 99% confidence interval [CI]) were applied to assess associations between both patient characteristics and follow-up with a primary care provider and/or cardiologist with the outcome of statin adherence change (increase or decrease) from the 6-month pre- to 6-month post-AMI periods. Of 113 296 patients, 64.0% had no change in adherence, while 19.7% had increased and 16.3% had decreased adherence after AMI hospitalization. Black and Hispanic patients were more likely to have either increased or decreased adherence than white patients. Patients who required coronary artery bypass graft surgery (OR, 1.34; 99% CI, 1.21-1.49) or percutaneous transluminal coronary angioplasty/stent procedure (OR, 1.25; 99% CI, 1.17-1.32) during their index hospitalization were more likely to have increased adherence. Follow-up with a primary care provider was only mildly associated with increased adherence (OR, 1.08; 99% CI, 1.00-1.16), while follow-up with a cardiologist (OR, 1.15; 99% CI, 1.05-1.25) or both provider types (OR, 1.21; 99% CI, 1.12-1.30) had stronger associations with increased adherence.
conclusionsPost-AMI changes in statin adherence varied by patient characteristics, and improved adherence was associated with post-discharge follow-up care, particularly with a cardiologist or both a primary care provider and a cardiologist.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.