Evidence map›Paper›PMID 29051053›Full record

ReviewSeminars in cell & developmental biology2018

Milk lipid regulation at the maternal-offspring interface.

Dengbao Yang, HoangDinh Huynh, Yihong Wan

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dengbao YangDepartment of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
HoangDinh HuynhDepartment of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Yihong WanDepartment of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: yihong.wan@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

Connection of Mineral and Energy Metabolism by the Nuclear Receptor PPAR-gammaR01DK089113 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI WAN, YIHONG · 2011 to 2015
$1.8M
NIDDK NIH HHS R01 DK089113
6 · The paper itself

Abstract

Milk lipids provide a large proportion of energy, nutrients, essential fatty acids, and signaling molecules for the newborns, the synthesis of which is a tightly controlled process. Dysregulated milk lipid production and composition may be detrimental to the growth, development, health and survival of the newborns. Many genetically modified animal models have contributed to our understanding of milk lipid regulation in the lactating mammary gland. In this review, we discuss recent advances in our knowledge of the mechanisms that control milk lipid biosynthesis and secretion during lactation, and how maternal genetic and dietary defects impact milk lipid composition and consequently offspring traits.

Indexed as

AnimalsAnimals, NewbornFemaleGene Expression RegulationLactationLipid MetabolismLipidsMammary Glands, AnimalMilkSterol Regulatory Element Binding ProteinsLipidsSterol Regulatory Element Binding ProteinsGenetic defectHigh fat dietInflammatory milkLactating mammary glandMilk lipid

Identifiers

PMID29051053
PMCPMC5916746
OpenAlexW2766630062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.