ReviewDevelopmental cognitive neuroscience2018
The conception of the ABCD study: From substance use to a broad NIH collaboration.
Review in Developmental cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 617 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
617 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Relationship Between Family History of Depression and Brain Structure and Function: A Systematic Review of Large Cohorts.Biological psychiatry · 2026Pooled it
- The Genetic Architecture of the Human Corpus Callosum and its Subregions.Nature communications · 2025Pooled it
- Enriched neighborhood environments relate to episodic memory through prefrontal rather than medial temporal pathways during late childhood and early adolescence.Brain and environment · 2026Article
- Outdoor Air Pollution, Perivascular Space Morphology, and Cognition in Preadolescence.Biological psychiatry global open science · 2026Article
- Executive functions as a transdiagnostic endophenotype in developmental psychopathology.Molecular psychiatry · 2026Review
- Multivariate associations between sleep patterns and self-regulation in adolescence: Canonical correlation analysis across ABCD and NCANDA cohorts.Chronobiology international · 2026Article
- Identifying significant environmental predictors of change in delay discounting among adolescents in the Adolescent Brain Cognitive Development Study.Experimental and clinical psychopharmacology · 2026Article
- Associations between prenatal alcohol exposure and parent-reported sleep disturbances in 10,336 adolescents: an Adolescent Brain Cognitive Development study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Cortical microarchitecture supports preadolescent functional brain network connectivity.bioRxiv : the preprint server for biology · 2026Article
- Polysubstance use disorders among US adults.Molecular psychiatry · 2026Article
- Substance use patterns from late childhood to mid-adolescence: Updates on the Adolescent Brain Cognitive Development Study.Drug and alcohol dependence reports · 2026Article
- Brain structural pathways linking dietary patterns and cognitive performance in adolescents.Brain structure & function · 2026Article
- Practical considerations for dense longitudinal neuroimaging: Ten simple rules for frequent scanning over short time periods.Developmental cognitive neuroscience · 2026Article
- Identification of comprehensive genetic factors, pathways, and shared genetic architecture of putamen volume in adolescent cohort.Translational psychiatry · 2026Article
- Family Conflict and Neighborhood Context in Latino Adolescent Depression: An ABCD Study.Research square · 2026Article
- ABCD-ReproNim: An educational program for responsible and reproducible analyses of ABCD data.Developmental cognitive neuroscience · 2026Article
- Contextualizing the adolescent social brain: Links to social health using data from the Adolescent Brain Cognitive Development Study.Developmental cognitive neuroscience · 2026Article
- The longitudinal structure of cognition in the ABCD study and associations with neural function and psychopathology: A Bayesian probabilistic principal components analysis.Developmental cognitive neuroscience · 2026Article
- Within- and between-study site variations in ambient air pollution exposure at ages 9-10 years in the Adolescent Brain Cognitive Development (ABCD) Study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Recreational Activities and Youth Outcomes: An Explainable Machine Learning Study.JAACAP open · 2026Article
557 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
22 authors.
Funding
Abstract
Adolescence is a time of dramatic changes in brain structure and function, and the adolescent brain is highly susceptible to being altered by experiences like substance use. However, there is much we have yet to learn about how these experiences influence brain development, how they promote or interfere with later health outcomes, or even what healthy brain development looks like. A large longitudinal study beginning in early adolescence could help us understand the normal variability in adolescent brain and cognitive development and tease apart the many factors that influence it. Recent advances in neuroimaging, informatics, and genetics technologies have made it feasible to conduct a study of sufficient size and scope to answer many outstanding questions. At the same time, several Institutes across the NIH recognized the value of collaborating in such a project because of its ability to address the role of biological, environmental, and behavioral factors like gender, pubertal hormones, sports participation, and social/economic disparities on brain development as well as their association with the emergence and progression of substance use and mental illness including suicide risk. Thus, the Adolescent Brain Cognitive Development study was created to answer the most pressing public health questions of our day.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.