Evidence map›Paper›PMID 29050958›Full record

ArticleRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2018

Metal artefact reduction for accurate tumour delineation in radiotherapy.

David Gergely Kovacs, Laura A Rechner, Ane L Appelt, Anne K Berthelsen, Junia C Costa, Jeppe Friborg, Gitte F Persson, Jens Peter Bangsgaard, Lena Specht, Marianne C Aznar

Abstract read
In one paragraph

Article in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Practical considerations for handling implants in proton therapy.Journal of applied clinical medical physics · 2025
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  17. Dental management in head and neck cancers: from intensity-modulated radiotherapy with photons to proton therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David Gergely KovacsDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Biomedical Engineering, Department of Electrical Engineering, Technical University of Denmark, Lyngby, Denmark. Electronic address: david.gergely.kovacs@regionh.dk.
Laura A RechnerDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Niels Bohr Institute, University of Copenhagen, Denmark.
Ane L AppeltDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Leeds Institute of Cancer and Pathology, University of Leeds, and Leeds Cancer Centre, St. James's University Hospital, UK.
Anne K BerthelsenDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet Copenhagen University Hospital, Denmark.
Junia C CostaDepartment of Radiology, Copenhagen University Hospital Herlev Gentofte, Denmark.
Jeppe FriborgDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark.
Gitte F PerssonDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark.
Jens Peter BangsgaardDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark.
Lena SpechtDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Marianne C AznarDepartment of Oncology, Copenhagen University Hospital Rigshospitalet, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, UK.

Funding

Cancer Research UK 21133Cancer Research UK C8225/A21133Medical Research Council MC_U137686858
6 · The paper itself

Abstract

background and purposeTwo techniques for metal artefact reduction for computed tomography were studied in order to identify their impact on tumour delineation in radiotherapy. MATERIALS AND

methodsUsing specially designed phantoms containing metal implants (dental, spine and hip) as well as patient images, we investigated the impact of two methods for metal artefact reduction on (A) the size and severity of metal artefacts and the accuracy of Hounsfield Unit (HU) representation, (B) the visual impact of metal artefacts on image quality and (C) delineation accuracy. A metal artefact reduction algorithm (MAR) and two types of dual energy virtual monochromatic (DECT VM) reconstructions were used separately and in combination to identify the optimal technique for each implant site.

resultsThe artefact area and severity was reduced (by 48-76% and 58-79%, MAR and DECT VM respectively) and accurate Hounsfield-value representation was increased by 22-82%. For each energy, the observers preferred MAR over non-MAR reconstructions (p < 0.01 for dental and hip cases, p < 0.05 for the spine case). In addition, DECT VM was preferred for spine implants (p < 0.01). In all cases, techniques that improved target delineation significantly (p < 0.05) were identified.

conclusionsDECT VM and MAR techniques improve delineation accuracy and the optimal of reconstruction technique depends on the type of metal implant.

Indexed as

AlgorithmsArtifactsBreast NeoplasmsCohort StudiesFemaleHeartHumansMetalsPhantoms, ImagingProspective StudiesProstheses and ImplantsRadiotherapy Planning, Computer-AssistedReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray ComputedMetalsDelineation uncertaintyDual energy CTIGRTIterative metal artefact reduction

Identifiers

PMID29050958
PMCPMC5864514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.