Evidence map›Paper›PMID 29050469›Full record

ArticleACS chemical neuroscience2018

In Vivo [

Matthias Schoenberger, Frederick A Schroeder, Michael S Placzek, Randall L Carter, Bruce R Rosen, Jacob M Hooker, Christin Y Sander

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Pharmacological Characterization of [Molecular imaging and biology · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. NMDA receptor ion channel activation detected in vivo with [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  9. A Review of Molecular Imaging of Glutamate Receptors.Molecules (Basel, Switzerland) · 2020
    Review
  10. Evaluation of the Novel PET Tracer [Molecular imaging and biology · 2019
    Article
  11. Review
  12. First in human evaluation of [EJNMMI research · 2018
    Article
  13. Simplifying [EJNMMI research · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Matthias SchoenbergerAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.
Frederick A SchroederAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.ORCID 0000-0003-0469-4196
Michael S PlaczekAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.
Randall L CarterGE Global Research , Niskayuna, New York 12309, United States.
Bruce R RosenAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.
Jacob M HookerAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.ORCID 0000-0002-9394-7708
Christin Y SanderAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Charlestown, Massachusetts 02129, United States.ORCID 0000-0001-6003-8615
Harvard University · USMassachusetts General Hospital · USGE Global Research (United States) · US

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Combined MRI/PET Imager for Simultaneous Acquisition of PET/MRI DataS10RR022976 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI JENKINS, BRUCE · 2007 to 2007
$2.0M
CYCLOTRON &RADIOCHEMISTRY: SUBSTANCE ABUSE, COCAINE, OPIOIDS10RR017208 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2004 to 2004
$500k
PET CAMERA FOR BRAIN IMAGING: SCHIZOPHRENIA, BIPOLAR DISORDERS10RR019933 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$500k
Carbon-11 Radiopharmaceutical Production SystemS10RR026666 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA · 2010 to 2010
$462k
Imaging dopamine receptor adaptations and signaling pathways with combined PET/fMRIK99DA043629 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SANDER, CHRISTIN Y. · 2017 to 2018
$372k
NCRR NIH HHS S10 RR017208NCRR NIH HHS S10 RR019933NCRR NIH HHS S10 RR022976NCRR NIH HHS S10 RR026666NIBIB NIH HHS P41 EB015896NIDA NIH HHS K99 DA043629
6 · The paper itself

Abstract

As one of the major excitatory ion channels in the brain, NMDA receptors have been a leading research target for neuroscientists, physicians, medicinal chemists, and pharmaceutical companies for decades. Molecular imaging of NMDA receptors by means of positron emission tomography (PET) with [

Indexed as

RadiopharmaceuticalsSulfhydryl CompoundsAnimalsBinding, CompetitiveBrainCerebrovascular CirculationDizocilpine MaleateDrug InteractionsExcitatory Amino Acid AntagonistsFluorine RadioisotopesHemodynamicsKetamineMacaca mulattaMagnetic Resonance ImagingMaleMethamphetamineDizocilpine MaleateExcitatory Amino Acid AntagonistsFluorine RadioisotopesifenprodilKetamineMethamphetaminePhencyclidinePiperidinesRadiopharmaceuticalsReceptors, N-Methyl-D-AspartateSulfhydryl Compounds[18F]GE-179neuroreceptor imagingNMDA receptorsPET/MRI

Identifiers

PMID29050469
PMCPMC5894869
OpenAlexW2766973546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.