ArticleOncotarget2017
Nomograms incorporated serum direct bilirubin level for predicting prognosis in stages II and III colorectal cancer after radical resection.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Bilirubin metabolism in relation to cancer.Frontiers in oncology · 2025Review
- Predictive value of direct bilirubin and total bile acid in lung adenocarcinoma patients treated with EGFR-TKIs.BMC pulmonary medicine · 2024Article
- Preoperative albumin-bilirubin score predicts short-term outcomes and long-term prognosis in colorectal cancer patients undergoing radical surgery.World journal of gastrointestinal surgery · 2024Article
- Serum Direct Bilirubin as a Biomarker for Breast Cancer.Breast cancer (Dove Medical Press) · 2024Article
- The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery.Canadian journal of gastroenterology & hepatology · 2023Article
- A nomogram based on pretreatment levels of serum bilirubin and total bile acid levels predicts survival in colorectal cancer patients.BMC cancer · 2021Article
- An Oxidative Stress Index-Based Score for Prognostic Prediction in Colorectal Cancer Patients Undergoing Surgery.Oxidative medicine and cellular longevity · 2021Article
- Association between Platelet Count with 1-year Survival in Patients with Cancer Cachexia.Journal of Cancer · 2021Article
- Article
- The prognostic impact of serum bilirubin in stage IV colorectal cancer patients.Journal of clinical laboratory analysis · 2018Article
- Article
- A nomogram based on serum bilirubin and albumin levels predicts survival in gastric cancer patients.Oncotarget · 2017Article
- Furanodienone induces G0/G1 arrest and causes apoptosis via the ROS/MAPKs-mediated caspase-dependent pathway in human colorectal cancer cells: a study in vitro and in vivo.Cell death & disease · 2017Article
- Is serum bilirubin level a predictor factor in parotid gland carcinoma?Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An elevated serum bilirubin has been reported to be associated with a reduced risk of some cancer; however, the prognostic significance of serum bilirubin in colorectal cancer wasn't fully understood. The purpose of this study was to evaluate whether serum bilirubin could predict the prognosis of patients in stages II and III colorectal cancer. A retrospective cohort of 986 patients with colorectal cancer who received surgical resection between January 2005 and December 2010 was included in the study. Levels for serum bilirubin were obtained from medical records. Survival analysis was used to evaluate the predictive value of bilirubin. Serum direct bilirubin (DBIL) was validated as a significant prognostic factor by univariate cox regression test for both overall survival (OS) and disease free survival (DFS) (
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