Evidence map›Paper›PMID 29050300›Full record

ArticleOncotarget2017

TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer.

Dai Yuedi, Cai Yuankun, Zhao Jiaying, Liu Han, Wang Yueqi, Liu Houbao, Zhang Dexiang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Oncoimmunology · 2025
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  8. The genetic and epigenetic regulation ofFrontiers in immunology · 2022
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dai YuediDepartment of Medical Oncology, Cancer Hospital of Fudan University, Minhang Branch, Shanghai 200240, China.
Cai YuankunGeneral Surgery Department, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Zhao JiayingGeneral Surgery Department, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Liu HanGeneral Surgery Department, General Surgery Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Wang YueqiGeneral Surgery Department, General Surgery Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Liu HoubaoGeneral Surgery Department, General Surgery Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Zhang DexiangGeneral Surgery Department, Zhongshan-Xuhui Hospital Affiliated to Fudan University, Shanghai 200031, China.
Fudan University · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant activation of beta-catenin/TCF (T-cell factor) signaling is frequently observed in the pancreatic cancer. However, the regulation of nuclear beta-catenin/TCF transcription machinery remains largely unknown. In this study, TFCP2 (transcriptional factor CP2) expression in pancreatic cancer was detected by qPCR, immunohistochemistry and western blot. Western blot, colony formation assay, migration and invasion experiment were performed to investigate the effects of TFCP2 on the growth and migration of pancreatic cancer cells.

Indexed as

beta-catenin/TCF signalingoncogenepancreatic cancerTFCP2

Identifiers

PMID29050300
PMCPMC5642575
OpenAlexW2740682600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.