Evidence map›Paper›PMID 29050294›Full record

ArticleOncotarget2017

The density of mast cells c-Kit

Michele Ammendola, Cosmo Damiano Gadaleta, Adam Enver Frampton, Tullio Piardi, Riccardo Memeo, Valeria Zuccalà, Maria Luposella, Rosa Patruno, Nicola Zizzo, Pietro Gadaleta and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Tryptase and tumor angiogenesis.Frontiers in oncology · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Role of Mast Cells in Shaping the Tumor Microenvironment.Clinical reviews in allergy & immunology · 2020
    Review
  14. Carcinogenesis: the cancer cell-mast cell connection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Michele AmmendolaDepartment of Medical and Surgical Sciences, Clinical Surgery Unit, University of Catanzaro "Magna Graecia" Medical School, Viale Europa-Germaneto, Catanzaro, Italy.
Cosmo Damiano GadaletaInterventional Radiology Unit with Integrated Section of Traslational Medical Oncology, National Cancer Research Centre, "Giovanni Paolo II", Bari, Italy.
Adam Enver FramptonHPB Surgical Unit, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital, London, UK.
Tullio PiardiDepartment of General, Digestive and Endocrine Surgery, Hopital Robert Debre, Centre Hospitalier Universitaire de Reims, Universite de Reims Champagne-Ardenne, Reims, France.
Riccardo MemeoHepato-Biliary and Pancreatic Surgical Unit, General, Digestive and Endocrine Surgery, IRCAD, IHU Mix-Surg, Institute for Minimally Invasive Image-Guided Surgery, University of Strasbourg, 1 place de l'Hôpital, Strasbourg, France.
Valeria ZuccalàPathology Unit, "Pugliese-Ciaccio" Hospital, Catanzaro, Italy.
Maria LuposellaCardiovascular Disease Unit, "San Giovanni di Dio" Hospital, Crotone, Italy.
Rosa PatrunoChair of Pathology, Veterinary Medical School, University "Aldo Moro", Bari, Italy.
Nicola ZizzoChair of Pathology, Veterinary Medical School, University "Aldo Moro", Bari, Italy.
Pietro GadaletaInterventional Radiology Unit with Integrated Section of Traslational Medical Oncology, National Cancer Research Centre, "Giovanni Paolo II", Bari, Italy.
Patrick PessauxHepato-Biliary and Pancreatic Surgical Unit, General, Digestive and Endocrine Surgery, IRCAD, IHU Mix-Surg, Institute for Minimally Invasive Image-Guided Surgery, University of Strasbourg, 1 place de l'Hôpital, Strasbourg, France.
Rosario SaccoDepartment of Medical and Surgical Sciences, Clinical Surgery Unit, University of Catanzaro "Magna Graecia" Medical School, Viale Europa-Germaneto, Catanzaro, Italy.
Giuseppe SammarcoDepartment of Medical and Surgical Sciences, Clinical Surgery Unit, University of Catanzaro "Magna Graecia" Medical School, Viale Europa-Germaneto, Catanzaro, Italy.
Girolamo RanieriInterventional Radiology Unit with Integrated Section of Traslational Medical Oncology, National Cancer Research Centre, "Giovanni Paolo II", Bari, Italy.
Istituto Tumori Bari · ITMagna Graecia University · ITUniversity of Bari Aldo Moro · ITAzienda Ospedaliera Pugliese Ciaccio · ITHammersmith Hospital · GBHôpital Robert-Debré · FRInstitut de Chirurgie Guidée par l'Image · FRNuovo Ospedale San Giovanni di Dio · ITUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Literature data suggest that inflammatory cells such as mast cells (MCs) are involved in angiogenesis. MCs can stimulate angiogenesis by releasing of well identified pro-angiogenic cytokines stored in their cytoplasm. In particular, MCs can release tryptase, a potent

Indexed as

angiogenesisc-Kit-receptormast cellspancreatic ductal adenocarcinomatryptase

Identifiers

PMID29050294
PMCPMC5642569
OpenAlexW2741922061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.