Evidence map›Paper›PMID 29050239›Full record

ArticleOncotarget2017

Application of

Sarah Rohde, Tobias Lindner, Stefan Polei, Jan Stenzel, Luise Borufka, Sophie Achilles, Eric Hartmann, Falko Lange, Claudia Maletzki, Michael Linnebacher and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Anatomical MRI and [Scientific reports · 2020
    Article
  6. NSG mice as hosts for oncological precision medicine.Laboratory investigation; a journal of technical methods and pathology · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Sarah RohdeDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Tobias LindnerCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Rostock, Germany.
Stefan PoleiCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Rostock, Germany.
Jan StenzelCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Rostock, Germany.
Luise BorufkaDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Sophie AchillesDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Eric HartmannDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Falko LangeOscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, Germany.
Claudia MaletzkiMolecular Oncology and Immunotherapy, Department of General Surgery, Rostock University Medical Center, Rostock, Germany.
Michael LinnebacherMolecular Oncology and Immunotherapy, Department of General Surgery, Rostock University Medical Center, Rostock, Germany.
Änne GlassInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Sarah Marie SchwarzenböckDepartment of Nuclear Medicine, Rostock University Medical Center, Rostock, Germany.
Jens KurthDepartment of Nuclear Medicine, Rostock University Medical Center, Rostock, Germany.
Alexander HohnDepartment of Nuclear Medicine, Rostock University Medical Center, Rostock, Germany.
Brigitte VollmarInstitute of Experimental Surgery, Rostock University Medical Center, Rostock, Germany.
Bernd Joachim KrauseDepartment of Nuclear Medicine, Rostock University Medical Center, Rostock, Germany.
Robert JasterDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatient-derived tumor cell lines are a powerful tool to analyze the sensitivity of individual tumors to specific therapies in mice. An essential prerequisite for such an approach are reliable quantitative techniques to monitor tumor progression

methodsWe have employed HROC24 cells, grown heterotopically in NMRI Foxn1

resultsRepeated measure ANOVA by a

conclusions5'-FU and PLX4720 were largely ineffective with respect to HROC24 tumor growth. Tumoral uptake of

Indexed as

5’-fluorouracilcolorectal cancerin vivo imagingmouse modelPLX4720

Identifiers

PMID29050239
PMCPMC5642514
OpenAlexW2735646232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.