Evidence map›Paper›PMID 29049547›Full record

ArticleJAMA surgery2018

Management of Stage I Squamous Cell Carcinoma of the Anal Canal.

Christy Y Chai, Hop S Tran Cao, Samir Awad, Nader N Massarweh

Erratum issued Registry-linked trialAbstract readComparative Study
In one paragraph

Article in JAMA surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02437851 (A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma), which is not on this map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02437851 phase2completednot on this map

A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma (SISCCA) of the Anal Canal and Perianus in HIV-Infected Persons

TypeinterventionalSponsorAIDS Malignancy ConsortiumRan2015 to 2026Enrolled16ConditionsAnal Squamous Cell Carcinoma, HIV Infection, Stage 0 Anal Canal Cancer, Stage I Anal Canal CancerArmsTherapeutic Conventional Surgery
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. SEOM-GEMCAD-TTD clinical guidelines for anal cancer (2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. Pooled it
  3. Guideline
  4. Outcome following local excision of T1 anal cancers-a systematic review.International journal of colorectal disease · 2020
    Pooled it
  5. Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2018
    Guideline
  6. Article
  7. Review
  8. Local excision for anal squamous cell carcinoma: challenges in patient selection and diagnosis.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Anal Cancer: The Past, Present and Future.Current oncology (Toronto, Ont.) · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Christy Y ChaiMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Hop S Tran CaoMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Samir AwadMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Nader N MassarwehMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChemoradiotherapyAdultAgedAnus NeoplasmsCarcinoma, Squamous CellDatabases, FactualFemaleHumansMaleMiddle AgedNeoplasm GradingNeoplasm StagingRetrospective StudiesSurvival RateTumor Burden

Identifiers

PMID29049547
PMCPMC5885927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.