ArticlePloS one2017
Synchrotron imaging and Markov Chain Monte Carlo reveal tooth mineralization patterns.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 57 citations in OpenAlex.
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- Enamel carbon, oxygen, and strontium isotopes reveal limited mobility in an extinct rhinoceros at Ashfall Fossil Beds, Nebraska, USA.Scientific reports · 2025Article
- Strontium isotope mapping of elephant enamel supports an integrated microsampling-modeling workflow to reconstruct herbivore migrations.Communications biology · 2025Article
- Role of amelogenin phosphorylation in regulating dental enamel formation.Matrix biology : journal of the International Society for Matrix Biology · 2024Article
- Comparison between strip sampling and laser ablation methods to infer seasonal movements from intra-tooth strontium isotopes profiles in migratory caribou.Scientific reports · 2023Article
- Putative avian teeth from the Late Cretaceous of Alberta, Canada, are more likely from crocodilians.PloS one · 2023Article
- A chimpanzee enamel-diet δJournal of human evolution · 2021Article
- Subarctic climate for the earliestScience advances · 2021Article
- An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures.Chemical science · 2021Article
- A robust, semi-automated approach for counting cementum increments imaged with synchrotron X-ray computed tomography.PloS one · 2021Article
- The hidden structure of human enamel.Nature communications · 2019Article
- Mapping the Tooth Enamel Proteome and Amelogenin Phosphorylation Onto Mineralizing Porcine Tooth Crowns.Frontiers in physiology · 2019Article
- The pay-off of hypsodonty - timing and dynamics of crown growth and wear in molars of Soay sheep.BMC evolutionary biology · 2018Article
- Wintertime stress, nursing, and lead exposure in Neanderthal children.Science advances · 2018Article
- Determinants of blood waterChemical geology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The progressive character of tooth formation records aspects of mammalian life history, diet, seasonal behavior and climate. Tooth mineralization occurs in two stages: secretion and maturation, which overlap to some degree. Despite decades of study, the spatial and temporal pattern of elemental incorporation during enamel mineralization remains poorly characterized. Here we use synchrotron X-ray microtomography and Markov Chain Monte Carlo sampling to estimate mineralization patterns from an ontogenetic series of sheep molars (n = 45 M1s, 18 M2s). We adopt a Bayesian approach that posits a general pattern of maturation estimated from individual- and population-level mineral density variation over time. This approach converts static images of mineral density into a dynamic model of mineralization, and demonstrates that enamel secretion and maturation waves advance at nonlinear rates with distinct geometries. While enamel secretion is ordered, maturation geometry varies within a population and appears to be driven by diffusive processes. Our model yields concrete expectations for the integration of physiological and environmental signals, which is of particular significance for paleoseasonality research. This study also provides an avenue for characterizing mineralization patterns in other taxa. Our synchrotron imaging data and model are available for application to multiple disciplines, including health, material science, and paleontological research.
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