ReviewAnesthesia and analgesia2017
Chronic Opioid Use After Surgery: Implications for Perioperative Management in the Face of the Opioid Epidemic.
Review in Anesthesia and analgesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 293 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Non-Randomized Interventional Pilot Study of the Effects of Early Administration of Ultrasound Guided Regional Anesthesia for Long Bone Fractures on Long Term Patient Opioid Usage
Using Difference-in-Differences to Evaluate the Effect of a Statewide Quality Improvement Program on New Persistent Opioid Use After Surgery
Effect of Perioperative Oral Pregabalin in Total Knee Replacement for Postoperative Pain
Intertransverse Process Block to Improve Quality of Recovery and Pain Management in Adult Cardiac Surgical Patients: a Prospective Double-Blinded Randomized Controlled Trial
SAVE Trial: SAfe Opioid Use Video Education
The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair
The Impact of Intraoperative Methadone on Postoperative Opioid Use
Who cites it
293 citing papers in PubMed, 5 syntheses or guidelines pooled it, 700 citations in OpenAlex.
- Erector Spinae Plane Block vs. Intercostal Nerve Block for Pain Management in Thoracic Surgeries and Chest Wall Traumas: A Meta-Analysis.Current pain and headache reports · 2026Pooled it
- Patient-related risk factors for new persistent opioid use after surgery among opioid-naïve individuals in the United States: a systematic review and meta-analysis.Pain medicine (Malden, Mass.) · 2026Pooled it
- Reducing Opioid Exposure Following Common Ambulatory Hand Surgery: A Systematic Review.Hand (New York, N.Y.) · 2025Pooled it
- Laparoscopic-assisted versus ultrasound-guided transversus abdominis plane block for laparoscopic cholecystectomy: a systematic review and meta-analysis.BMC surgery · 2024Pooled it
- Effect of perioperative intravenous ibuprofen versus acetaminophen on postoperative opioid consumption and pain after general anesthesia: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials.Korean journal of anesthesiology · 2024Pooled it
- Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis.Anaesthesia · 2026Trial
- Effectiveness of intra-articular analgesia in reducing postoperative pain after minimally invasive sacroiliac joint fusion: a double-blind randomized controlled trial.Scientific reports · 2024Trial
- Efficacy and Safety of Paragastric Neural Blockade in Controlling Pain, Nausea, and Vomiting After Sleeve Gastrectomy: A Randomized Controlled Trial.Obesity surgery · 2024Trial
- Perioperative Intravenous Dexamethasone Significantly Reduces Postoperative Opioid Requirement and Nausea After Unilateral Elective Hip Arthroscopy: A Randomized Double-blinded Placebo-controlled Trial.The American journal of sports medicine · 2024Trial
- Nurse initiated auricular acupressure for post-operative pain control in patients undergoing TKA or THA: A randomized controlled trial.International journal of orthopaedic and trauma nursing · 2024Trial
- Trial
- Comparison of the Analgesic Efficacy of Opioid-Sparing Multimodal Analgesia and Morphine-Based Patient-Controlled Analgesia in Minimally Invasive Surgery for Colorectal Cancer.World journal of surgery · 2022Trial
- Brain-based measures of nociception during general anesthesia with remifentanil: A randomized controlled trial.PLoS medicine · 2022Trial
- High-dose steroids in high pain responders undergoing total knee arthroplasty: a randomised double-blind trial.British journal of anaesthesia · 2022Trial
- Evaluation of pain and opioid consumption in local preemptive anesthesia and the erector spine plane block in thoracoscopic surgery: A randomized clinical trial.Revista do Colegio Brasileiro de Cirurgioes · 2022Trial
- Dorsal penile block of bupivacaine with adjuvant dexmedetomidine and dexamethasone can safely improve immediate post-operative analgesia and decrease opioid consumption after inflatable penile prosthesis surgery.International journal of impotence research · 2026Article
- Precision postoperative pain management: A multidimensional matter.Journal of perioperative practice · 2026Article
- Article
- Individualizing Perioperative Analgesia: Patient-Specific Determinants of Postoperative Pain and Opioid-Related Outcomes.Medicina (Kaunas, Lithuania) · 2026Review
- Enhanced Recovery for Patients Undergoing Metabolic Bariatric Surgery in a Community Hospital: A Retrospective Pre-Post Quality Improvement Study.Obesity surgery · 2026Article
233 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Physicians, policymakers, and researchers are increasingly focused on finding ways to decrease opioid use and overdose in the United States both of which have sharply increased over the past decade. While many efforts are focused on the management of chronic pain, the use of opioids in surgical patients presents a particularly challenging problem requiring clinicians to balance 2 competing interests: managing acute pain in the immediate postoperative period and minimizing the risks of persistent opioid use after the surgery. Finding ways to minimize this risk is particularly salient in light of a growing literature suggesting that postsurgical patients are at increased risk for chronic opioid use. The perioperative care team, including surgeons and anesthesiologists, is poised to develop clinical- and systems-based interventions aimed at providing pain relief in the immediate postoperative period while also reducing the risks of opioid use longer term. In this paper, we discuss the consequences of chronic opioid use after surgery and present an analysis of the extent to which surgery has been associated with chronic opioid use. We follow with a discussion of the risk factors that are associated with chronic opioid use after surgery and proceed with an analysis of the extent to which opioid-sparing perioperative interventions (eg, nerve blockade) have been shown to reduce the risk of chronic opioid use after surgery. We then conclude with a discussion of future research directions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.