Evidence map›Paper›PMID 29048998›Full record

ArticleZebrafish2018

Transmission of Pseudoloma neurophilia in Laboratory Zebrafish (Danio rerio) When Using Mass Spawning Chambers and Recommendations for Chamber Disinfection.

Samantha M Peneyra, Jose Cardona-Costa, Julie White, Christopher M Whipps, Elyn R Riedel, Neil S Lipman, Christine Lieggi

Open access · greenAbstract read
In one paragraph

Article in Zebrafish, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Recent Advances with Fish Microsporidia.Experientia supplementum (2012) · 2022
    Article
  3. Testing Alternative Surface Disinfection Agents for Zebrafish (Journal of the American Association for Laboratory Animal Science : JAALAS · 2021
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Samantha M Peneyra1 Tri-Institutional Training Program in Laboratory Animal Medicine and Science , New York, New York.
Jose Cardona-Costa2 Center of Comparative Medicine and Pathology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine , New York, New York.
Julie White1 Tri-Institutional Training Program in Laboratory Animal Medicine and Science , New York, New York.
Christopher M Whipps3 Department of Environment and Forest Biology, State University of New York College of Environmental Science and Forestry , Syracuse, New York.
Elyn R Riedel4 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center , New York, New York.
Neil S Lipman1 Tri-Institutional Training Program in Laboratory Animal Medicine and Science , New York, New York.
Christine Lieggi1 Tri-Institutional Training Program in Laboratory Animal Medicine and Science , New York, New York.
Memorial Sloan Kettering Cancer Center · USWeill Cornell Medicine · USCornell University · USSUNY College of Environmental Science and Forestry · USTri-Institutional PhD Program in Chemical Biology · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Control of Diseases in Zebrafish Research FacilitiesR24OD010998 · OD · OREGON STATE UNIVERSITY · PI KENT, MICHAEL LAWRENCE · 2012 to 2021
$3.0M
NCI NIH HHS P30 CA008748NIH HHS R24 OD010998
6 · The paper itself

Abstract

Pseudoloma neurophilia, a microsporidium that primarily infects neural tissues, is a common pathogen in laboratory zebrafish. The risk of parasite transmission with different spawning apparatuses and the effectiveness of disinfection are unknown. In this study, we spawned uninfected zebrafish with P. neurophilia-infected zebrafish in either 50 L mass spawning chambers (MSCs) or 1 L standard breeding tanks (BTs). Fish were spawned once or thrice, with and without chamber disinfection between uses, to evaluate risk of vertical and horizontal transmission. Six disinfection protocols were tested to determine which effectively eliminated residual spores. We demonstrated that three consecutive uses of an MSC significantly increased the risk of transmission to other fish when compared to the use of BTs or only one spawning event in an MSC (both p < 0.0001). Vertical transmission was not detected with any method. Disinfection with ∼100 ppm bleach soak (pH ∼7.0), 75 ppm Wescodyne

Indexed as

Animal HusbandryAnimalsAnimals, LaboratoryDisinfectionFish DiseasesMicrosporidiaMicrosporidiosisZebrafishdisinfectionmass spawning chambermicrosporidianPseudoloma neurophiliatransmissionzebrafish

Identifiers

PMID29048998
PMCPMC5792237
OpenAlexW2765963093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.