Evidence map›Paper›PMID 29048937›Full record

ReviewAnnals of the American Thoracic Society2017

Executive Summary of the NHLBI Workshop Report: Leveraging Current Scientific Advancements to Understand Sarcoidosis Variability and Improve Outcomes.

Lisa A Maier, Elliott D Crouser, William J Martin, Jerry Eu

Abstract readReview
In one paragraph

Review in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Discovery of Two Novel Immunoepitopes and Development of a Peptide-based Sarcoidosis Immunoassay.American journal of respiratory and critical care medicine · 2024
    Article
  6. Observational
  7. Article
  8. Article
  9. The Role of Oxidative Stress in Sarcoidosis.International journal of molecular sciences · 2021
    Review
  10. Epigenetics and sarcoidosis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  11. Article
  12. Application of Proteomics in Sarcoidosis.American journal of respiratory cell and molecular biology · 2020
    Review
  13. Article
  14. Article
  15. Comprehensive Care for Patients with Sarcoidosis.Journal of clinical medicine · 2020
    Review
  16. Review
  17. Article
  18. Potential immunotherapies for sarcoidosis.Expert opinion on biological therapy · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lisa A Maier1 Division of Environmental and Occupational Health Sciences, National Jewish Health, Denver, Colorado.
Elliott D Crouser3 Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, and.
William J Martin4 College of Public Health, Ohio State University, Wexner Medical Center, Columbus, Ohio; and.
Jerry Eu5 Division of Lung Diseases, National Heart, Lung, and Blood Institute, Bethesda, Maryland.

Funding

Immunologic and Molecular Phenotypes in AATD and SarcoidosisU01HL112695 · NHLBI · NATIONAL JEWISH HEALTH · PI MAIER, LISA A · 2012 to 2014
$465k
NHLBI NIH HHS U01 HL112695
6 · The paper itself

Abstract

Sarcoidosis is a systemic granulomatous disease that primarily affects the lung; it is associated with significant disparities, more commonly impacting those in the prime of their lives (age 20-50 yr, with a second peak after age 60 yr), black individuals, and women. However, the burden of disease, the ability to diagnose and prognose organ involvement and course, as well as specific treatment options, management options, and disease pathogenesis remain poorly understood. As a result, the National Heart, Lung, and Blood Institute undertook a sarcoidosis workshop, "Leveraging Current Scientific Advancements to Understand Sarcoidosis Variability and Improve Outcomes," to help address these issues by defining the scientific and clinical priorities to improve sarcoidosis care. The overarching recommendations from this workshop are outlined in the following summary and detailed in the accompanying articles. The recommendations included establishing collaborations and networks to conduct research based on consensus definitions of disease phenotypes and standards of care, and to provide clinical outreach to areas with a burden of disease to improve care. These collaborative networks would also serve as the hub to conduct clinical trials of devastating phenotypes (e.g., cardiac, neurologic, and fibrotic disease) not only for treatment but to enhance our understanding of the burden of disease. In addition, the networks would be used to leverage state-of-the-art "omics" and systems biology research, as well as other studies to advance understanding of disease pathogenesis, and development of biomarkers and therapeutic targets, with a goal to translate this information to improve care of individuals with sarcoidosis.

Indexed as

Biomedical ResearchHumansNational Heart, Lung, and Blood Institute (U.S.)SarcoidosisUnited StatesdisparitiesNHLBIsarcoidosisworkshop

Identifiers

PMID29048937
PMCPMC5802571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.