ArticleJournal of natural products2018
Antiplasmodial Chromanes and Chromenes from the Monotypic Plant Species Koeberlinia spinosa.
Article in Journal of natural products, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Structure, biological activity, and biosynthesis of natural chromanes and chromenes.Archives of pharmacal research · 2025Review
- One-Pot Synthesis of Thiochromen-4-ones from 3-(Arylthio)propanoic Acids.Chemistry (Basel, Switzerland) · 2025Article
- Research progress on heteroterpene and meroterpenoid compounds from theFrontiers in pharmacology · 2025Review
- Stereochemistry of Chiral 2-Substituted Chromanes: Twist of the Dihydropyran Ring and Specific Optical Rotation.Molecules (Basel, Switzerland) · 2023Article
- Synthesis and Structural Characterization of 1-(ACS omega · 2021Article
- Enantioselective Cleavage of Cyclobutanols Through Ir-Catalyzed C-C Bond Activation: Mechanistic and Synthetic Aspects.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Computational insight into the mechanism and origin of high regioselectivity in the ring-opening cyclization of spirocyclopropanes with stabilized sulfonium ylides by the DFT.Journal of molecular modeling · 2020Article
- Galtonosides A-E: Antiproliferative and Antiplasmodial Cholestane Glycosides fromJournal of natural products · 2020Article
- Stachybotrychromenes A-C: novel cytotoxic meroterpenoids from Stachybotrys sp.Mycotoxin research · 2018Article
- Raistrickiones A-E from a Highly Productive Strain ofMarine drugs · 2018Article
- Synthesis and Evaluation of Thiochroman-4-One Derivatives as Potential Leishmanicidal Agents.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Nine new compounds containing either a chromane or chromene ring moiety were isolated from the monotypic plant Koeberlinia spinosa. Compounds 1-4 are chromanes with all possible E and Z isomers of the isoprenoid side chain, with compound 5 a methylated derivative of 1. Compounds 6 and 7 were assigned as diastereomeric cyclized derivatives of 2 and were probably artifacts formed during the extraction or the isolation processes. Compounds 8 and 9 were characterized as new chromenes. Structure elucidation of 1-9 was conducted via 1D and 2D NMR spectroscopic data interpretation, and absolute configurations were determined by ECD spectroscopic analysis. Compounds 2, 5, 6, and 7 had weak antiplasmodial activity, while none of the compounds exhibited antiproliferative activity. The isolation, structure elucidation, and biological evaluation of these compounds are presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.