Evidence map›Paper›PMID 29048518›Full record

ArticleJournal of pediatric psychology2018

Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis.

Mary K Lynch, Margaux J Barnes, Reed A Dimmitt, Lisa Martin, Marc E Rothenberg, Burel R Goodin

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of pediatric psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. The Cellie Coping Kit for children with Eosinophilic Esophagitis: Feasibility, acceptability, and preliminary outcomes.Journal of child health care : for professionals working with children in the hospital and community · 2023
    Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. New Developments in the Diagnosis and Treatment of Eosinophilic Esophagitis.Current treatment options in gastroenterology · 2019
    Review
  13. Article
  14. Observational
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mary K LynchDepartment of Psychology.
Margaux J BarnesDepartment of Pediatrics, University of Alabama at Birmingham.
Reed A DimmittDepartment of Pediatrics, University of Alabama at Birmingham.
Lisa MartinDepartment of Pediatrics, University of Cincinnati School of Medicine.
Marc E RothenbergDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center.
Burel R GoodinDepartment of Psychology.
University of Alabama at Birmingham · USCincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

TSLP, IL-9-producing mucosal mast cells, and allergic inflammationU19AI070235 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Jocelyn M Biagini · 2006 to 2026
$31.3M
Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Kathryn Ann Wikenheiser-Brokamp · 2007 to 2026
$24.4M
NIAID NIH HHS U19 AI070235NIDDK NIH HHS P30 DK078392NIMHD NIH HHS L60 MD010798
6 · The paper itself

Abstract

Objective: To evaluate relations between health-related quality of life (HRQoL) and clinical symptom presentation in youth with eosinophilic esophagitis (EoE). We hypothesized that presence of dysphagia, reflux, nausea/vomiting, and epigastric pain would be related to poorer HRQoL. In predictive models, it was hypothesized that dysphagia, reflux, nausea/vomiting, and epigastric pain would each significantly and uniquely predict poorer HRQoL. Methods: This cross-sectional, two-study design included 91 dyads comprised children with EoE and their respective caregivers across two tertiary children's hospitals, Site 1 in the Midwest (N = 47) and Site 2 in the Deep South (N = 44). Youth and their caregivers both completed questionnaires addressing HRQoL and EoE symptoms during clinic visits. Results: Per youth self-report, epigastric pain was found to be a significant predictor of poor physical and psychosocial HRQoL. Per caregiver-proxy reports, epigastric pain was found to be a significant predictor of poor physical HRQoL. Conclusions: The clinical symptoms of EoE, specifically epigastric pain, were found to be predictive of the youth's HRQoL. Targeted interventions to help youth with EoE better manage their specific symptom experiences could ultimately improve HRQoL.

Indexed as

Quality of LifeAbdominal PainAdolescentChildChild, PreschoolCross-Sectional StudiesEosinophilic EsophagitisFemaleHumansMale

Identifiers

PMID29048518
PMCPMC6059136
OpenAlexW2762418943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.