Evidence map›Paper›PMID 29048396›Full record

ArticleSensors (Basel, Switzerland)2017

Time Multiplexed Active Neural Probe with 1356 Parallel Recording Sites.

Bogdan C Raducanu, Refet F Yazicioglu, Carolina M Lopez, Marco Ballini, Jan Putzeys, Shiwei Wang, Alexandru Andrei, Veronique Rochus, Marleen Welkenhuysen, Nick van Helleputte and 7 more

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. A Thin Film Transistor Backplane for Scalable Chronic Neural Interfaces.bioRxiv : the preprint server for biology · 2026
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  12. Direct-Print 3D Electrodes for Large-Scale, High-Density, and Customizable Neural Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bogdan C RaducanuImec, 3001 Leuven, Belgium. raducanu@imec.be.
Refet F YaziciogluImec, 3001 Leuven, Belgium. firatyazicioglu@gmail.com.
Carolina M LopezImec, 3001 Leuven, Belgium. moralope@imec.be.
Marco BalliniImec, 3001 Leuven, Belgium. Marco.Ballini@imec.be.ORCID 0000-0001-7442-8497
Jan PutzeysImec, 3001 Leuven, Belgium. Jan.Putzeys@imec.be.
Shiwei WangImec, 3001 Leuven, Belgium. Shiwei.Wang@imec.be.ORCID 0000-0002-5450-2108
Alexandru AndreiImec, 3001 Leuven, Belgium. Alexandru.Andrei@imec.be.
Veronique RochusImec, 3001 Leuven, Belgium. Veronique.Rochus@imec.be.
Marleen WelkenhuysenImec, 3001 Leuven, Belgium. Marleen.Welkenhuysen@imec.be.
Nick van HelleputteImec, 3001 Leuven, Belgium. Nick.VanHelleputte@imec.be.
Silke MusaImec, 3001 Leuven, Belgium. Silke.Musa@imec.be.
Robert PuersImec, 3001 Leuven, Belgium. robert.puers@esat.kuleuven.be.
Fabian KloostermanFaculty of Psychology and Educational Sciences, KU Leuven, 3000 Leuven, Belgium. Chris.VanHoof@imec.be.
Chris van HoofImec, 3001 Leuven, Belgium. Fabian.Kloosterman@nerf.be.
Richárd FiáthInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1117 Budapest, Hungary. fiath.richard@ttk.mta.hu.ORCID 0000-0001-8732-2691
István UlbertInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1117 Budapest, Hungary. ulbert.istvan@ttk.mta.hu.ORCID 0000-0001-9941-9159
Srinjoy MitraSchool of Engineering, University of Glasgow, Glasgow G10 8QQ, UK. srinjoy.mitra@glasgow.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a high electrode density and high channel count CMOS (complementary metal-oxide-semiconductor) active neural probe containing 1344 neuron sized recording pixels (20 µm × 20 µm) and 12 reference pixels (20 µm × 80 µm), densely packed on a 50 µm thick, 100 µm wide, and 8 mm long shank. The active electrodes or pixels consist of dedicated in-situ circuits for signal source amplification, which are directly located under each electrode. The probe supports the simultaneous recording of all 1356 electrodes with sufficient signal to noise ratio for typical neuroscience applications. For enhanced performance, further noise reduction can be achieved while using half of the electrodes (678). Both of these numbers considerably surpass the state-of-the art active neural probes in both electrode count and number of recording channels. The measured input referred noise in the action potential band is 12.4 µVrms, while using 678 electrodes, with just 3 µW power dissipation per pixel and 45 µW per read-out channel (including data transmission).

Indexed as

active electrodeactive neural probesCMOShigh density componentneural amplifierneural arrayneural recording

Identifiers

PMID29048396
PMCPMC5677417

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.