Evidence map›Paper›PMID 29046993›Full record

ArticleNanoscale research letters2017

Synthesis and In Vitro Performance of Polypyrrole-Coated Iron-Platinum Nanoparticles for Photothermal Therapy and Photoacoustic Imaging.

Thi Tuong Vy Phan, Nhat Quang Bui, Madhappan Santha Moorthy, Kang Dae Lee, Junghwan Oh

Abstract read
In one paragraph

Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thi Tuong Vy PhanMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, Republic of Korea.
Nhat Quang BuiMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, Republic of Korea.
Madhappan Santha MoorthyMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, Republic of Korea.
Kang Dae LeeDepartment of Otolaryngology - Head and Neck Surgery, Kosin University College of Medicine, Busan, 49267, Republic of Korea.
Junghwan OhMarine-Integrated Bionics Research Center, Pukyong National University, Busan, 48513, Republic of Korea. jungoh@pknu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multifunctional nano-platform for the combination of photo-based therapy and photoacoustic imaging (PAI) for cancer treatment has recently attracted much attention to nanotechnology development. In this study, we developed iron-platinum nanoparticles (FePt NPs) with the polypyrrole (PPy) coating as novel agents for combined photothermal therapy (PTT) and PAI. The obtained PPy-coated FePt NPs (FePt@PPy NPs) showed excellent biocompatibility, photothermal stability, and high near-infrared (NIR) absorbance for the combination of PTT and PAI. In vitro investigation experimentally demonstrated the effectiveness of FePt@PPy NPs in killing cancer cells with NIR laser irradiation. Moreover, the phantom test of PAI used in conjunction with FePt@PPy NPs showed a strong photoacoustic signal. Thus, the novel FePt@PPy NPs could be considered as promising multifunctional nanoparticles for further applications of photo-based diagnosis and treatment.

Indexed as

Cancer treatmentIron-platinum nanoparticlesphotoacoustic imagingPhotothermal therapyPolypyrrole

Identifiers

PMID29046993
PMCPMC5647319

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.