Evidence map›Paper›PMID 29046835›Full record

ArticleBeilstein journal of nanotechnology2017

Carbon nano-onions as fluorescent on/off modulated nanoprobes for diagnostics.

Stefania Lettieri, Marta d'Amora, Adalberto Camisasca, Alberto Diaspro, Silvia Giordani

Abstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Modulation of Efficient Diiodo-BODIPYFrontiers in chemistry · 2020
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefania LettieriNano Carbon Materials, Istituto Italiano di Tecnologia (IIT), via Livorno 60, 10144, Turin, Italy.
Marta d'AmoraNanoscopy, Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Adalberto CamisascaNano Carbon Materials, Istituto Italiano di Tecnologia (IIT), via Livorno 60, 10144, Turin, Italy.
Alberto DiasproNanoscopy, Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Silvia GiordaniNano Carbon Materials, Istituto Italiano di Tecnologia (IIT), via Livorno 60, 10144, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multishell fullerenes, known as carbon nano-onions (CNOs), have emerged as a platform for bioimaging because of their cell-penetration properties and minimal systemic toxicity. Here, we describe the covalent functionalization of CNOs with a π-extended distyryl-substituted boron dipyrromethene (BODIPY) dye with on/off modulated fluorescence emission activated by an acidic environment. The switching properties are linked to the photoinduced electron transfer (PET) characteristics of the dimethylamino functionalities attached to the BODIPY core. The on/off emission of the fluorescent CNOs is fast and reversible both in solution and in vitro, making this nanomaterial suitable as pH-dependent probes for diagnostic applications.

Indexed as

carbon nanomaterialsfluorescenceimagingnanomedicinenano-onion

Identifiers

PMID29046835
PMCPMC5629398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.