Evidence map›Paper›PMID 29046823›Full record

ArticleBiomaterials research2017

Functionalization of Ti-40Nb implant material with strontium by reactive sputtering.

Markus Göttlicher, Marcus Rohnke, Yannik Moryson, Jürgen Thomas, Joachim Sann, Anja Lode, Matthias Schumacher, Romy Schmidt, Stefan Pilz, Annett Gebert and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Mass Spectrometry Imaging of Biomaterials.Materials (Basel, Switzerland) · 2023
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Markus GöttlicherInstitute of Physical Chemistry and Center of Materials Research, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 17, 35392, Giessen, Germany.
Marcus RohnkeInstitute of Physical Chemistry and Center of Materials Research, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 17, 35392, Giessen, Germany.ORCID 0000-0002-8867-950X
Yannik MorysonInstitute of Physical Chemistry and Center of Materials Research, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 17, 35392, Giessen, Germany.
Jürgen ThomasIFW Dresden, Institute for Complex Materials, Helmholtzstrasse 20, 01069 Dresden, Germany.
Joachim SannInstitute of Physical Chemistry and Center of Materials Research, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 17, 35392, Giessen, Germany.
Anja LodeCentre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Matthias SchumacherCentre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Romy SchmidtIFW Dresden, Institute for Complex Materials, Helmholtzstrasse 20, 01069 Dresden, Germany.
Stefan PilzIFW Dresden, Institute for Complex Materials, Helmholtzstrasse 20, 01069 Dresden, Germany.
Annett GebertIFW Dresden, Institute for Complex Materials, Helmholtzstrasse 20, 01069 Dresden, Germany.
Thomas GemmingIFW Dresden, Institute for Complex Materials, Helmholtzstrasse 20, 01069 Dresden, Germany.
Jürgen JanekInstitute of Physical Chemistry and Center of Materials Research, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 17, 35392, Giessen, Germany.
Justus-Liebig-Universität Gießen · DELeibniz Institute for Solid State and Materials Research · DETechnische Universität Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurface functionalization of orthopedic implants with pharmaceutically active agents is a modern approach to enhance osseointegration in systemically altered bone. A local release of strontium, a verified bone building therapeutic agent, at the fracture site would diminish side effects, which could occur otherwise by oral administration. Strontium surface functionalization of specially designed titanium-niobium (Ti-40Nb) implant alloy would provide an advanced implant system that is mechanically adapted to altered bone with the ability to stimulate bone formation.

methodsStrontium-containing coatings were prepared by reactive sputtering of strontium chloride (SrCl

resultsDense coatings, consisting of SrO

conclusionsTi-40Nb alloy, a potential orthopedic implant material for osteoporosis patients, could be successfully plasma coated with a dense SrO

Indexed as

BiocompatibilityOsteoporosisPlasma depositionStrontium releaseSurface coatingTitanium alloy

Identifiers

PMID29046823
PMCPMC5634847
OpenAlexW2763419259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.