Evidence map›Paper›PMID 29046783›Full record

ArticleAntimicrobial resistance and infection control2017

Phenotypic and genotypic characteristics of ESBL and AmpC producing organisms associated with bacteraemia in Ho Chi Minh City, Vietnam.

Nguyen Phu Huong Lan, Nguyen Huu Hien, Tu Le Thi Phuong, Duy Pham Thanh, Nga Tran Vu Thieu, Dung Tran Thi Ngoc, Ha Thanh Tuyen, Phat Voong Vinh, Matthew J Ellington, Guy E Thwaites and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. A review and meta-analysis of non-typhoidalOne health (Amsterdam, Netherlands) · 2024
    Review
  6. Article
  7. Molecular detection of blaAnnals of clinical microbiology and antimicrobials · 2021
    Article
  8. Virulence and Antibiotic Resistance Characteristics ofFrontiers in cellular and infection microbiology · 2021
    Article
  9. PathogenicAntibiotics (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Article
  12. Prevalence of Potentially Pathogenic Antibiotic-ResistantApplied and environmental microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Nguyen Phu Huong Lan *The Hospital for Tropical Diseases, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam.
Nguyen Huu Hien *The Hospital for Tropical Diseases, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam.
Tu Le Thi PhuongOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Duy Pham ThanhOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Nga Tran Vu ThieuOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Dung Tran Thi NgocOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Ha Thanh TuyenOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Phat Voong VinhOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Matthew J EllingtonAntimicrobial Resistance and Healthcare Associated Infection Unit, National Infection Service, Public Health England, Public Health England, London, UK.
Guy E ThwaitesOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Nguyen Van Vinh ChauThe Hospital for Tropical Diseases, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam.
Stephen BakerOxford University Clinical Research Unit, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
Christine J BoinettThe Hospital for Tropical Diseases, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam.
Oxford University Clinical Research Unit · VNHospital for Tropical Diseases · VNPublic Health England · GBUniversity of Cambridge · GBUniversity of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundBroad-spectrum antimicrobials are commonly used as empirical therapy for infections of presumed bacterial origin. Increasing resistance to these antimicrobial agents has prompted the need for alternative therapies and more effective surveillance. Better surveillance leads to more informed and improved delivery of therapeutic interventions, potentially leading to better treatment outcomes.

methodsWe screened 1017 Gram negative bacteria (excluding

resultsPhenotypic screening found that 304/1017 (30%) organisms were resistance to third generation cephalosporins; 172/1017 (16.9%) of isolates exhibited ESBL activity, 6.2% (63/1017) had AmpC activity, and 0.5% (5/1017) had both ESBL and AmpC activity.

conclusionAmpC and ESBL producing organisms were commonly associated with bloodstream infections in this setting, with antimicrobial resistant organisms being equally distributed between infections originating from the community and healthcare settings.

Indexed as

AmpCAntimicrobial resistanceBacteraemiaESBL

Identifiers

PMID29046783
PMCPMC5644090
OpenAlexW2766867303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.