Evidence map›Paper›PMID 29046644›Full record

ArticleFrontiers in physiology2017

More Relaxation by Deep Breath on Methacholine- Than on Exercise-Induced bronchoconstriction during the Routine Testing of Asthmatic Children.

Iulia Ioan, Aurélie Tatopoulos, Stéphanie Metche, Laurianne Coutier, Emmanuelle Houriez, Sébastien Kiefer, Aurore Blondé, Claude Bonabel, François Marchal, Jocelyne Derelle and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Iulia IoanService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Aurélie TatopoulosService de Pédiatrie, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Stéphanie MetcheService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Laurianne CoutierService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Emmanuelle HouriezService de Pédiatrie, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Sébastien KieferService de Pédiatrie, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Aurore BlondéService de Pédiatrie, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Claude BonabelService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
François MarchalService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Jocelyne DerelleService de Pédiatrie, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Cyril E SchweitzerService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Silvia Demoulin-AlexikovaService d'explorations Fonctionnelles Pédiatriques, Hôpital d'enfants, CHRU de Nancy, Vandœuvre-lès-Nancy, France.
Hôpital d'Enfants · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep inspiration (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation. The hypothesis was tested that DI induces more relaxation in methacholine induced bronchoconstriction-solely determined by the smooth muscle contraction-than in exercise induced bronchoconstriction, which is contributed to by both smooth muscle contraction and airway wall inflammation. The respiratory conductance (Grs) response to DI was monitored in asthmatic children presenting a moderately positive airway response to challenge by methacholine (

Indexed as

airway mechanicsbronchial inflammationchildhood asthmaforced oscillationslung hysteresis

Identifiers

PMID29046644
PMCPMC5632680
OpenAlexW2761576145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.