Evidence map›Paper›PMID 29046636›Full record

ReviewFrontiers in pharmacology2017

Targeting the Immune System with Plant Lectins to Combat Microbial Infections.

Jannyson J B Jandú, Roberval N Moraes Neto, Adrielle Zagmignan, Eduardo M de Sousa, Maria C A Brelaz-de-Castro, Maria T Dos Santos Correia, Luís C N da Silva

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Pharmacological and Clinical Efficacy ofMolecules (Basel, Switzerland) · 2022
    Review
  7. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Immunoadjuvant and Humoral Immune Responses of Garlic (Molecules (Basel, Switzerland) · 2022
    Article
  10. Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Structure-function and application of plant lectins in disease biology and immunity.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jannyson J B JandúDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Roberval N Moraes NetoPós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, Brazil.
Adrielle ZagmignanPós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, Brazil.
Eduardo M de SousaPós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, Brazil.
Maria C A Brelaz-de-CastroNúcleo de Enfermagem, Universidade Federal de Pernambuco, Vitória de Santo Antão, Brazil.
Maria T Dos Santos CorreiaDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Luís C N da SilvaPós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, Brazil.
Centro Universitário do Maranhão · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The arsenal of drugs available to treat infections caused by eukaryotic and prokaryotic microbes has been declining exponentially due to antimicrobial resistance phenomenon, leading to an urgent need to develop new therapeutic strategies. Host-directed immunotherapy has been reported as an attractive option to treat microbial infections. It consists in the improvement of host defenses by increasing the expression of inflammatory mediators and/or controlling of inflammation-induced tissue injury. Although the

Indexed as

adjuvantshost–parasite interactionimmunizationimmunomodulatory lectinsnew treatments

Identifiers

PMID29046636
PMCPMC5632806
OpenAlexW2764286180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.