Evidence map›Paper›PMID 29046443›Full record

ArticleJournal of virology2018

Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.

Hideyuki Hara, Hironori Miyata, Nandita Rani Das, Junji Chida, Tatenobu Yoshimochi, Keiji Uchiyama, Hitomi Watanabe, Gen Kondoh, Takashi Yokoyama, Suehiro Sakaguchi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. PrPInternational journal of biological sciences · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Hideyuki Hara *Division of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan.
Hironori Miyata *Animal Research Center, School of Medicine, University of Occupational and Environmental Health, Yahatanishi, Kitakyushu, Japan.
Nandita Rani Das *Division of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan.
Junji ChidaDivision of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan.
Tatenobu YoshimochiDivision of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan.
Keiji UchiyamaDivision of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan.
Hitomi WatanabeLaboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Gen KondohLaboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Takashi YokoyamaNational Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan.
Suehiro SakaguchiDivision of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan sakaguchi@tokushima-u.ac.jp.
Tokushima University · JPKyoto University · JPNational Agriculture and Food Research Organization · JPUniversity of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conformational conversion of the cellular isoform of prion protein, PrP

Indexed as

Disease SusceptibilityAnimalsBrainCattleEncephalopathy, Bovine SpongiformHumansMiceMice, TransgenicOligopeptidesPrion DiseasesPrionsPrPC ProteinsSequence DeletionOligopeptidesPrionsPrPC Proteinsbovine spongiform encephalopathyBSEoctapeptide repeatprionprion proteinscrapie

Identifiers

PMID29046443
PMCPMC5730770
OpenAlexW2919491176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.