Evidence map›Paper›PMID 29046411›Full record

ArticleJournal of clinical microbiology2018

Rapid Detection and Differentiation of Clinically Relevant Candida Species Simultaneously from Blood Culture by Use of a Novel Signal Amplification Approach.

Wanyuan Ao, Joshua Klonoski, Eric Berlinghoff, Jordan Jensen, Taliman Afroz, Denton Munns, Wes Lindsey, Gerald Denys, Robert Jenison

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecular Diagnosis of Yeast Infections.Current fungal infection reports · 2021
    Review
  2. Identification ofPathogens (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wanyuan AoGreat Basin Scientific, Salt Lake City, Utah, USA wanyuan.ao@gmail.com.
Joshua KlonoskiUniversity of Utah Department of Pathology, Salt Lake City, Utah, USA.
Eric BerlinghoffGreat Basin Scientific, Salt Lake City, Utah, USA.
Jordan JensenGreat Basin Scientific, Salt Lake City, Utah, USA.
Taliman AfrozGreat Basin Scientific, Salt Lake City, Utah, USA.
Denton MunnsGreat Basin Scientific, Salt Lake City, Utah, USA.
Wes LindseyGreat Basin Scientific, Salt Lake City, Utah, USA.
Gerald DenysIndiana University School of Medicine, Indianapolis, Indiana, USA.
Robert JenisonGreat Basin Scientific, Salt Lake City, Utah, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal bloodstream infections are a significant problem in the United States, with an attributable mortality rate of up to 40%. An early diagnosis to direct appropriate therapy has been shown to be critical to reduce mortality rates. Conventional phenotypic methods for fungal detection take several days, which is often too late to impact outcomes. Herein, we describe a cost-effective multiplex assay platform for the rapid detection and differentiation of major clinically relevant

Indexed as

Nucleic Acid Amplification TechniquesBiotinCandidaCandidemiaDNA, FungalHumansMolecular Diagnostic TechniquesReproducibility of ResultsRNA, Ribosomal, 28SSensitivity and SpecificityTime FactorsBiotinDNA, FungalRNA, Ribosomal, 28SAMPEDblood cultureCandidaCandida detectionmolecular diagnosticssignal amplification

Identifiers

PMID29046411
PMCPMC5744229

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.