Evidence map›Paper›PMID 29046343›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Complement Activation in Peritoneal Dialysis-Induced Arteriolopathy.

Maria Bartosova, Betti Schaefer, Justo Lorenzo Bermejo, Silvia Tarantino, Felix Lasitschka, Stephan Macher-Goeppinger, Peter Sinn, Bradley A Warady, Ariane Zaloszyc, Katja Parapatics and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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  20. Proteomic Research in Peritoneal Dialysis.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 4 countries.

Maria BartosovaDivision of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine.
Betti SchaeferDivision of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine.
Justo Lorenzo BermejoDepartment of Medical Biometry, Institute of Medical Biometry and Informatics, and.
Silvia TarantinoDepartment of Pediatrics and Adolescent Medicine and.
Felix LasitschkaDepartment of General Pathology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
Stephan Macher-GoeppingerDepartment of Pathology, University Medical Center Mainz, Mainz, Germany.
Peter SinnDepartment of General Pathology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
Bradley A WaradyDivision of Pediatric Nephrology, Children's Mercy Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
Ariane ZaloszycDepartment of Pediatrics 1, University Hospital of Strasbourg, Strasbourg, France.
Katja ParapaticsCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; and.
Peter MájekCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; and.
Keiryn L BennettCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; and.
Jun OhDepartment of Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christoph AufrichtDepartment of Pediatrics and Adolescent Medicine and.
Franz SchaeferDivision of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine.
Klaus KratochwillDepartment of Pediatrics and Adolescent Medicine and.
Claus Peter SchmittDivision of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, claus.peter.schmitt@med.uni-heidelberg.de.
German Center for Pediatric and Adolescent Rheumatology · DECeMM Research Center for Molecular Medicine · ATHeidelberg University · DEAustrian Academy of Sciences · ATMedical University of Vienna · ATUniversität Hamburg · DEUniversité de Strasbourg · FRUniversity Medical Center of the Johannes Gutenberg University Mainz · DEUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the leading cause of increased mortality in patients with CKD and is further aggravated by peritoneal dialysis (PD). Children are devoid of preexisting CVD and provide unique insight into specific uremia- and PD-induced pathomechanisms of CVD. We obtained peritoneal specimens from children with stage 5 CKD at time of PD catheter insertion (CKD5 group), children with established PD (PD group), and age-matched nonuremic controls (

Indexed as

Complement ActivationAdolescentArteriolesCase-Control StudiesChildChild, PreschoolComplement C1qComplement C3dComplement Membrane Attack ComplexComplement System ProteinsFemaleGene OntologyHumansInfantInfant, NewbornKidney Failure, ChronicComplement C1qComplement C3dComplement Membrane Attack ComplexComplement System ProteinsProteomeSmad2 ProteinSMAD2 protein, humanSmad3 ProteinSMAD3 protein, humanTransforming Growth Factor betaVascular Endothelial Growth Factor AVEGFA protein, humanarteriosclerosischildrencomplementperitoneal dialysisTGF-betavascular disease

Identifiers

PMID29046343
PMCPMC5748916
OpenAlexW2765547517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.