Evidence map›Paper›PMID 29046309›Full record

ArticleClinical and vaccine immunology : CVI2017

Stable Chromosomal Expression of Shigella flexneri 2a and 3a O-Antigens in the Live Salmonella Oral Vaccine Vector Ty21a.

Madushini N Dharmasena, Manuel Osorio, Kazuyo Takeda, Scott Stibitz, Dennis J Kopecko

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Human vaccines & immunotherapeutics · 2026
    Review
  2. Genetic engineering ofEcoSal Plus · 2024
    Review
  3. Toward aInternational journal of molecular sciences · 2023
    Review
  4. Review
  5. Recent Progress inPathogens (Basel, Switzerland) · 2021
    Review
  6. Review
  7. Synthesis and delivery ofProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. mBio · 2019
    Article
  12. Regulated DelayedTheranostics · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Madushini N DharmasenaLaboratory of Mucosal Pathogens and Cellular Immunology, U.S. FDA-Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA Madushini.Dharmasena@fda.hhs.gov.ORCID http://orcid.org/0000-0003-4954-2487
Manuel OsorioLaboratory of Mucosal Pathogens and Cellular Immunology, U.S. FDA-Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Kazuyo TakedaMicroscopy and Imaging Core Facility, U.S. FDA-Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Scott StibitzLaboratory of Mucosal Pathogens and Cellular Immunology, U.S. FDA-Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Dennis J KopeckoLaboratory of Mucosal Pathogens and Cellular Immunology, U.S. FDA-Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.
Center for Biologics Evaluation and Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have been exploring the use of the live attenuated

Indexed as

Drug CarriersGene ExpressionGenetic VectorsAnimalsAntibodies, BacterialBacteriophagesCloning, MolecularDisease Models, AnimalDysentery, BacillaryFemaleGenomic InstabilityMice, Inbred BALB CO AntigensPolysaccharides, BacterialSalmonella typhiShigella flexneriAntibodies, BacterialDrug CarriersO AntigensPolysaccharides, BacterialShigella VaccinesTy21a typhoid vaccineTyphoid-Paratyphoid VaccinesVaccines, Attenuatedlive vector vaccinesSalmonellaShigellaTy21a

Identifiers

PMID29046309
PMCPMC5717188
OpenAlexW2766211707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.