Evidence map›Paper›PMID 29046298›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Identification of dual mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial biogenesis.

Whitney S Gibbs, Sara M Garrett, Craig C Beeson, Rick G Schnellmann

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. 5-HTFrontiers in cellular neuroscience · 2024
    Article
  12. Review
  13. Article
  14. Review
  15. FDA-approved 5-HTExperimental neurology · 2021
    Article
  16. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Whitney S GibbsDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina , Charleston, South Carolina.
Sara M GarrettDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina , Charleston, South Carolina.
Craig C BeesonDepartment of Drug Discovery and Biomedical Sciences, Medical University of South Carolina , Charleston, South Carolina.
Rick G SchnellmannDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona , Tucson, Arizona.
Medical University of South Carolina · USUniversity of Arizona · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
SOUTH CAROLINA COBRE IN OXIDANTS, REDOX BALANCE AND STRESS SIGNALINGP20GM103542 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MADAN, LALIMA KATYAYANI · 2012 to 2020
$20.2M
MUSC Minority Student Development ProgramR25GM072643 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ERGUL, ADVIYE, RINKER, JENNIFER ANNE · 2005 to 2023
$5.8M
Mitochondrial Biogenesis Promotes Recovery From Oxidant InjuryR01GM084147 · NIGMS · UNIVERSITY OF ARIZONA · PI SCHNELLMANN, RICK G · 2008 to 2016
$2.4M
Training in Bioenergetics, Oxidative Stress and Metabolic SyndromeT32DK083262 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LEMASTERS, JOHN J · 2009 to 2018
$1.5M
5-HT Stimulation of Mitochondrial Biogenesis and Acute Kidney InjuryI01BX000851 · VA · SOUTHERN ARIZONA VA HEALTH CARE SYSTEM · PI SCHNELLMANN, RICK G · 2011 to 2025
–
BLRD VA I01 BX000851NIDDK NIH HHS T32 DK083262NIEHS NIH HHS P30 ES006694NIGMS NIH HHS P20 GM103542NIGMS NIH HHS R01 GM084147NIGMS NIH HHS R25 GM072643
6 · The paper itself

Abstract

Our laboratory recently made the novel observation that 5-hydroxytryptamine 1F (5-HT

Indexed as

Organelle BiogenesisAnimalsCarbazolesCells, CulturedFemaleFluorobenzenesIntracellular Signaling Peptides and ProteinsKidney Tubules, ProximalMitochondriaPhosphorylationRabbitsReceptor, Serotonin, 5-HT1FReceptors, SerotoninSecond Messenger SystemsSerotonin 5-HT1 Receptor AgonistsCarbazolesFluorobenzenesIntracellular Signaling Peptides and ProteinsLY 344864Receptor, Serotonin, 5-HT1FReceptors, SerotoninSerotonin 5-HT1 Receptor Agonists5-HTAktERKextracellular signal regulated kinaseGPCRG protein-coupled receptormitochondriaprotein kinase Bserotonin

Identifiers

PMID29046298
PMCPMC5866450
OpenAlexW2765373097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.