Evidence map›Paper›PMID 29046154›Full record

ReviewCurrent neuropharmacology2018

Neural Network Alterations Across Eating Disorders: A Narrative Review of fMRI Studies.

Trevor Steward, Jose M Menchon, Susana Jiménez-Murcia, Carles Soriano-Mas, Fernando Fernandez-Aranda

2 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current neuropharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 87 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 11 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05347914 nacompletednot on this mapstarted 2022, after this paper: background citation

Mobile Mindfulness Intervention to Reduce Non-Homeostatic Food Cravings in Emotional Eaters: Research Pilot

TypeinterventionalSponsorMcGill UniversityRan2022 to 2023Enrolled49ConditionsEmotional EatingArmsMindfulness
NCT06138782 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2026Enrolled20ConditionsAnorexia NervosaArmsRepetitive Transcranial Magnetic Stimulation (rTMS)
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 11 syntheses or guidelines pooled it, 153 citations in OpenAlex.

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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Trevor StewardDepartment of Psychiatry, University Hospital of Bellvitge -IDIBELL, Barcelona, Spain.
Jose M MenchonDepartment of Psychiatry, University Hospital of Bellvitge -IDIBELL, Barcelona, Spain.
Susana Jiménez-MurciaDepartment of Psychiatry, University Hospital of Bellvitge -IDIBELL, Barcelona, Spain.
Carles Soriano-MasDepartment of Psychiatry, University Hospital of Bellvitge -IDIBELL, Barcelona, Spain.
Fernando Fernandez-ArandaDepartment of Psychiatry, University Hospital of Bellvitge -IDIBELL, Barcelona, Spain.
Institut d'Investigació Biomédica de Bellvitge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional magnetic resonance imaging (fMRI) has provided insight on how neural abnormalities are related to the symptomatology of the eating disorders (EDs): anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED). More specifically, an increasingly growing number of brain imaging studies has shed light on how functionally connected brain networks contribute not only to disturbed eating behavior, but also to transdiagnostic alterations in body/interoceptive perception, reward processing and executive functioning.

methodsThis narrative review aims to summarize recent advances in fMRI studies of patients with EDs by highlighting studies investigating network alterations that are shared across EDs. RESULTS AND

conclusionFindings on reward processing in both AN and BN patients point to the presence of altered sensitivity to salient food stimuli in striatal regions and to the possibility of hypothalamic inputs being overridden by top-down emotional-cognitive control regions. Additionally, innovative new lines of research suggest that increased activations in fronto-striatal circuits are strongly associated with the maintenance of restrictive eating habits in AN patients. Although significantly fewer studies have been carried out in patients with BN and BED, aberrant neural responses to both food cues and anticipated food receipt appear to occur in these populations. These altered responses, coupled with diminished recruitment of prefrontal cognitive control circuitry, are believed to contribute to the binge eating of palatable foods. Results from functional network connectivity studies are diverse, but findings tend to converge on indicating disrupted resting-state connectivity in executive networks, the default-mode network and the salience network across EDs.

Indexed as

AnimalsBrainFeeding and Eating DisordersHumansMagnetic Resonance ImagingNeural Pathwaysanorexiabinge eating disorderbulimiaEating disordersfMRIneuroimaging.

Identifiers

PMID29046154
PMCPMC6187750
OpenAlexW2766441616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.