ArticleImmunity2017
Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8
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Article in Immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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0cells of the map it votes in
47citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
What it found
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Who cites it
47 citing papers in PubMed, 61 citations in OpenAlex.
- Epigenetic scars of CD8Nature immunology · 2021Trial
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- T cell adaptation in chronic infections and tumors.Cellular & molecular immunology · 2026Review
- Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection.Nature communications · 2025Article
- Chromatin landscape alteration uncovers multiple transcriptional circuits during memory CD8+ T-cell differentiation.Protein & cell · 2025Article
- Detection of anti-HCV antibodies in the clinical classification and epidemiological surveillance of HCV infection.Molecular biology reports · 2025Review
- Targeting archetypes of viral-driven cancers with immunotherapy: a perspective on immunogenicity within the tumor microenvironment.Frontiers in immunology · 2025Review
- Importance of Michaelis Constants for Cancer Cell Redox Balance and Lactate Secretion-Revisiting the Warburg Effect.Cancers · 2024Review
- Biomarkers in Detection of Hepatitis C Virus Infection.Pathogens (Basel, Switzerland) · 2024Review
- Hepatitis C Virus and the Host: A Mutual Endurance Leaving Indelible Scars in the Host's Immunity.International journal of molecular sciences · 2023Review
- Article
- Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.PLoS pathogens · 2023Article
- Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Review
- Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C.Nature communications · 2022Article
- CD8Frontiers in immunology · 2022Article
- T cell responses during HBV and HCV infections: similar but not quite the same?Current opinion in virology · 2021Review
- Elevated glycolysis imparts functional ability to CD8Life science alliance · 2021Article
- CD8Nature reviews. Immunology · 2021Review
Corrections and comments
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Authors and funding
20 authors at 8 institutions in 4 countries.
David WolskiGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Inserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg 67000, France; Université de Strasbourg, Strasbourg 67081, France.
Peter K FooteGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Diana Y ChenGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Lia L Lewis-XimenezLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040, Brazil.
Catherine FauvelleInserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg 67000, France; Université de Strasbourg, Strasbourg 67081, France.
Jasneet AnejaGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Andreas WalkerInstitute for Virology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany.
Pierre TonnerreGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Almudena Torres-CornejoGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Daniel KvistadGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Sabrina ImamDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Michael T WaringRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Damien C TullyRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Todd M AllenRagon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Raymond T ChungGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Jörg TimmInstitute for Virology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany.
W Nicholas HainingDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Arthur Y KimDivision of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Thomas F BaumertInserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg 67000, France; Université de Strasbourg, Strasbourg 67081, France; Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, Strasbourg 67000, France.
Georg M LauerGastrointestinal Unit and Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: glauer@mgh.harvard.edu.
Massachusetts General Hospital · USHarvard University · USDüsseldorf University Hospital · DERagon Institute of MGH, MIT and Harvard · USFundação Oswaldo Cruz · BRHoward Hughes Medical Institute · USInserm · FRInstitute for Translational Medicine and Liver Disease
Funding
Virology CoreU19AI082630 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG, GEORG Michael LAUER · 2009 to 2026
$48.1MPilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3MAcute Hepatitis C Infection in Young InjectorsR01DA016017 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAGE, KIMBERLY · 2002 to 2018
$14.0MThe role of NK cells during acute HCV infection and antiviral therapyU19AI066345 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KIM, ARTHUR Y · 2005 to 2014
$8.5MCD4+ T Cells in Acute Versus Chronic HCV InfectionR01AI105035 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAUER, GEORG MICHAEL · 2013 to 2017
$2.3MImmune Control and Evadion during Acute HCV InfectionU01AI131314 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAUER, GEORG MICHAEL · 2016 to 2020
$1.4MEuropean Research Council 671231Howard Hughes Medical InstituteNIAID NIH HHS R01 AI105035NIAID NIH HHS U01 AI131314NIAID NIH HHS U19 AI066345NIAID NIH HHS U19 AI082630NIDA NIH HHS R01 DA016017NIDDK NIH HHS P30 DK043351
Abstract
Distinct molecular pathways govern the differentiation of CD8
Indexed as
Acute DiseaseAdaptive ImmunityAdultAgedCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCluster AnalysisFemaleGene Expression ProfilingGene Regulatory NetworksGenetic VariationHepacivirusHepatitis C, ChronicHumansLymphocyte ActivationMaleadaptive immunityCD4 T cell helpCD8 T cellshepatitis C virusmetabolismnetwork analysisnucleosomeT cell dysfunctiontranscriptional regulationviral escape
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.