Evidence map›Paper›PMID 29045651›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Clinical decision support alert malfunctions: analysis and empirically derived taxonomy.

Adam Wright, Angela Ai, Joan Ash, Jane F Wiesen, Thu-Trang T Hickman, Skye Aaron, Dustin McEvoy, Shane Borkowsky, Pavithra I Dissanayake, Peter Embi and 8 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Development and application of desiderata for automated clinical ordering.Journal of the American Medical Informatics Association : JAMIA · 2025
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. A scoping review of rule-based clinical decision support malfunctions.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  13. A lightweight xAI approach to cervical cancer classification.Medical & biological engineering & computing · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Clinical decision support malfunctions related to medication routes: a case series.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Adam WrightDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Angela AiDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Joan AshDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR, USA.
Jane F WiesenDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR, USA.
Thu-Trang T HickmanDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Skye AaronDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Dustin McEvoyClinical and Quality Analysis, Partners Healthcare, Somerville, MA, USA.
Shane BorkowskyDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Pavithra I DissanayakeDepartment of Pathology, University of Illinois at Chicago, Chicago, IL, USA.
Peter EmbiRegenstrief Institute, Indianapolis, IN, USA.
William GalanterDepartment of Medicine, Pharmacy Practices, and Pharmacy Systems, Outcomes and Policy, University of Illinois at Chicago, Chicago, IL, USA.
Jeremy HarperDepartment of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Steve Z KassakianDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR, USA.
Rachel RamoniDepartment of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA, USA.
Richard SchreiberDepartment of Medicine and Information Technology, Holy Spirit Hospital - A Geisinger Affiliate, Camp Hill, PA, USA.
Anwar SirajuddinDepartment of Medical Informatics, Memorial Hermann Health System, Houston, TX, USA.
David W BatesDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Dean F SittigDepartment of Biomedical Informatics, University of Texas Health Science Center at Houston, TX, USA.

Funding

Improving clinical decision support reliability using anomaly detection methodsR01LM011966 · NLM · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WRIGHT, ADAM T · 2014 to 2017
$2.4M
NLM NIH HHS R01 LM011966
6 · The paper itself

Abstract

Objective: To develop an empirically derived taxonomy of clinical decision support (CDS) alert malfunctions. Materials and Methods: We identified CDS alert malfunctions using a mix of qualitative and quantitative methods: (1) site visits with interviews of chief medical informatics officers, CDS developers, clinical leaders, and CDS end users; (2) surveys of chief medical informatics officers; (3) analysis of CDS firing rates; and (4) analysis of CDS overrides. We used a multi-round, manual, iterative card sort to develop a multi-axial, empirically derived taxonomy of CDS malfunctions. Results: We analyzed 68 CDS alert malfunction cases from 14 sites across the United States with diverse electronic health record systems. Four primary axes emerged: the cause of the malfunction, its mode of discovery, when it began, and how it affected rule firing. Build errors, conceptualization errors, and the introduction of new concepts or terms were the most frequent causes. User reports were the predominant mode of discovery. Many malfunctions within our database caused rules to fire for patients for whom they should not have (false positives), but the reverse (false negatives) was also common. Discussion: Across organizations and electronic health record systems, similar malfunction patterns recurred. Challenges included updates to code sets and values, software issues at the time of system upgrades, difficulties with migration of CDS content between computing environments, and the challenge of correctly conceptualizing and building CDS. Conclusion: CDS alert malfunctions are frequent. The empirically derived taxonomy formalizes the common recurring issues that cause these malfunctions, helping CDS developers anticipate and prevent CDS malfunctions before they occur or detect and resolve them expediently.

Indexed as

Decision Support Systems, ClinicalEquipment Failure AnalysisMedical Order Entry SystemsClassificationEquipment FailureHumansMedical Records Systems, ComputerizedUnited States

Identifiers

PMID29045651
PMCPMC6019061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.