Evidence map›Paper›PMID 29045461›Full record

ArticlePloS one2017

Past alcohol consumption and incident atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study.

Shalini Dixit, Alvaro Alonso, Eric Vittinghoff, Elsayed Z Soliman, Lin Y Chen, Gregory M Marcus

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Alcohol and Atrial Fibrillation.Reviews in cardiovascular medicine · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shalini DixitCardiac Electrophysiology Section, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States of America.
Alvaro AlonsoDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, United States of America.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States of America.
Elsayed Z SolimanDepartment of Epidemiology, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Lin Y ChenCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, United States of America.
Gregory M MarcusCardiac Electrophysiology Section, Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States of America.

Funding

Mechanistic Relationships Between Ethanol and Human Atrial FibrillationR01AA022222 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREGORY M MARCUS · 2014 to 2026
$4.4M
Clinical and Transtional Science InstituteTL1TR000144 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$643k
American Heart Association-American Stroke Association 16EIA26410001NCATS NIH HHS TL1 TR000144NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNIAAA NIH HHS R01 AA022222
6 · The paper itself

Abstract

backgroundAlthough current alcohol consumption is a risk factor for incident atrial fibrillation (AF), the more clinically relevant question may be whether alcohol cessation is associated with a reduced risk. METHODS AND

resultsWe studied participants enrolled in the Atherosclerosis Risk in Communities Study (ARIC) between 1987 and 1989 without prevalent AF. Past and current alcohol consumption were ascertained at baseline and at 3 subsequent visits. Incident AF was ascertained via study ECGs, hospital discharge ICD-9 codes, and death certificates. Of 15,222 participants, 2,886 (19.0%) were former drinkers. During a median follow-up of 19.7 years, there were 1,631 cases of incident AF, 370 occurring in former consumers. Former drinkers had a higher rate of AF compared to lifetime abstainers and current drinkers. After adjustment for potential confounders, every decade abstinent from alcohol was associated with an approximate 20% (95% CI 11-28%) lower rate of incident AF; every additional decade of past alcohol consumption was associated with a 13% (95% CI 3-25%) higher rate of AF; and every additional drink per day during former drinking was associated with a 4% (95% CI 0-8%) higher rate of AF.

conclusionsAmong former drinkers, the number of years of drinking and the amount of alcohol consumed may each confer an increased risk of AF. Given that a longer duration of abstinence was associated with a decreased risk of AF, earlier modification of alcohol use may have a greater influence on AF prevention.

Indexed as

Alcohol DrinkingAtherosclerosisAtrial FibrillationFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedRisk Factors

Identifiers

PMID29045461
PMCPMC5646789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.