Evidence map›Paper›PMID 29045423›Full record

ArticlePloS one2017

Candidemia in non-ICU surgical wards: Comparison with medical wards.

Antonio Vena, Emilio Bouza, Maricela Valerio, Belén Padilla, José Ramón Paño-Pardo, Mario Fernández-Ruiz, Ana Díaz Martín, Miguel Salavert, Alessandra Mularoni, Mireia Puig-Asensio and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Evaluation of candidemia risk factors andSaudi medical journal · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Prognostic factors ofLancet regional health. Americas · 2022
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Persistent Candidemia in adults: underlying causes and clinical significance in the antifungal stewardship era.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  17. Meropenem antimicrobial stewardship program: clinical, economic, and antibiotic resistance impact.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Antonio VenaClinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Emilio BouzaClinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Maricela ValerioClinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Belén PadillaClinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
José Ramón Paño-PardoHospital Universitario La Paz, Madrid, Spain.
Mario Fernández-RuizHospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain.
Ana Díaz MartínServicio Andaluz de Salud, UGC-SCCU, Sevilla, Andalucía, Spain.
Miguel SalavertHospital Universitario y Politécnico La Fe, Valencia, Spain.
Alessandra MularoniIstituto mediterraneo per i trapianti e terapie ad alta specializzazione ISMETT-UPMC, Palermo, Italy.
Mireia Puig-AsensioHospital Universitario Vall d'Hebron, Barcelona, Spain.
Patricia MuñozClinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID http://orcid.org/0000-0001-5706-5583
CANDIPOP Project
Universidad Complutense de Madrid · ESAndalusian Health Service · ESHospital General Universitario Gregorio Marañón · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario La Paz · ESIstituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione · ITResearch Institute Hospital 12 de Octubre · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candidemia acquired outside critical care or hematological areas has received much attention in recent years; however, data on candidemia in surgical departments are very scarce. Our objectives were to describe episodes of candidemia diagnosed in surgical wards and to compare them with episodes occurring in medical wards. We performed a post hoc analysis of a prospective, multicenter study implemented in Spain during 2010-2011 (CANDIPOP project). Of the 752 episodes of candidemia, 369 (49.1%) occurred in patients admitted to surgical wards (165, 21.9%) or medical wards (204, 27.2%). Clinical characteristics associated with surgical patients were solid tumor as underlying disease, recent surgery, indwelling CVC, and parenteral nutrition. Candidemia was more commonly related to a CVC in the surgical than in the medical wards. The CVC was removed more frequently and early management was more appropriate within 48 hours of blood sampling in the surgical patients. Overall, 30-day mortality in the surgical departments was significantly lower than in medical wards (37.7% vs. 15.8%, p<0.001). Multivariate analysis revealed admission to a surgical ward and appropriate early management of candidemia as factors independently associated with a better outcome. We found that approximately 50% of episodes of candidemia occurred in non-hematological patients outside the ICU and that clinical outcome was better in patients admitted to surgical wards than in those hospitalized in medical wards. These findings can be explained by the lower severity of underlying disease, prompt administration of antifungal therapy, and central venous catheter removal.

Indexed as

Intensive Care UnitsAdultAgedCandidemiaDemographyFemaleHospitalizationHumansLogistic ModelsMaleMultivariate AnalysisPatients' RoomsRisk FactorsSurgical Procedures, OperativeTreatment Outcome

Identifiers

PMID29045423
PMCPMC5646772
OpenAlexW2766376791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.